Endoplasmic Reticulum Stress in Chronic Respiratory Diseases

NCT ID: NCT01211015

Last Updated: 2010-09-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-07-31

Brief Summary

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Aim: To investigate whether ER stress is implicated in the pathogenesis of various pulmonary disorders

Measurement:

1. Unfolded protein responses (UPRs) in blood (PBMCs)of patients

1. CHOP
2. GRP 78 and so on
2. Unfolded protein responses (UPRs) in blood (PBMCs)of healthy controls

1. CHOP
2. GRP 78 and so on

Detailed Description

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Conditions

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ER Stress, Chronic Airway Disorders, Lung Cancer, Interstitial Lung Diseases

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Control group

healthy control group

No interventions assigned to this group

Disease group

asthma, COPD, ILD, lung malignancy

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* \> 18 yrs
* Definitive diagnosis as chronic pulmonary diseases by physician

Exclusion Criteria

* Any other chronic medical illness such as DM, HTN, and other malignancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Chonbuk National University

OTHER

Sponsor Role lead

Responsible Party

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Chonbuk National University Medical School

Locations

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Chonbuk National University Hospital

Jeonju, Jeollabuk-do, South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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Yong Chul Lee, MD, phD

Role: CONTACT

Phone: 82-63-250-1664

Email: [email protected]

Facility Contacts

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Yong Chul Lee, MD, PhD

Role: primary

Other Identifiers

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RCPD ER stress

Identifier Type: -

Identifier Source: org_study_id