Acceptability and Feasibility of Human Papilloma Virus Vaccine

NCT ID: NCT01209338

Last Updated: 2010-09-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

1000 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-11-30

Study Completion Date

2010-12-31

Brief Summary

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The overall program goal is to determine the Acceptability and Feasibility of introducing a population based Human Papilloma Virus (HPV) Vaccination programme and understanding the key individual and community factors that would determine the potential acceptability of the vaccine.

Detailed Description

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The eligible participant will be chosen by door-door household visit. Each participant will be given information regarding the study and written informed consent will be obtained from them. Their participation will be entirely voluntary and no pressure or coercion will be used. Our team will help them with questions that are not well understood by them or are ambiguous for them. The questionnaire is in 2 sections. Section one will try and ascertain the mother's Knowledge, Attitude and Perception regarding cervix cancer, HPV infection and HPV Vaccination.

Section 1 will be interviewed for a period of 5-10 minutes followed by an information sheet providing details on HPV infection, its association with cervix cancer and HPV Vaccination against cervix cancer. The information sheet available will be explained to them for a period of 10-15 minutes. Our social workers will be available at all times to allay their misinterpretations. This will be followed by section 2 which will be a post intervention questionnaire comprising of questions regarding their attitude towards HPV vaccination and identifying barriers and motivators for these women towards vaccination.

The post-intervention questionnaire would be interviewed for a period of 10-15 minutes, thus a total of 25-40 minutes will be made available to every participant for the entire session. The team is expected to cover 15 women per day totaling to 300 women per month considering the monthly holidays and time lost in certain administrative issues.

Patients will be recruited for 4 months which will be followed by data entry, data analysis, formulation of results and write -up. Thus the entire study will last for eight months. The questionnaire consists of mostly close ended questions with options in the form of yes/no/do not know. Some questions which require definitive answers have been provided with plausible options. Some questions have been left open ended so as to avoid ambiguity. The questionnaire is simple, in continuity and is translated into Hindi and Marathi languages so as to meet the needs of the local population.

Conditions

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Cervical Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

NONE

Study Groups

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sensitized group

One arm will be a sensitized group which would have received cancer health awareness sessions and / or screening earlier at least once in the past.

Group Type ACTIVE_COMPARATOR

Health education

Intervention Type BEHAVIORAL

Health education about HPV infection, HPV vaccine and cervix cancer.

non-sensitized group

The second arm will belong to an area which has never been exposed to any form of cancer awareness or screening activities thus this group is a completely non-sensitized group.

Group Type NO_INTERVENTION

Health education

Intervention Type BEHAVIORAL

Health education about HPV infection, HPV vaccine and cervix cancer.

Interventions

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Health education

Health education about HPV infection, HPV vaccine and cervix cancer.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

All married women bearing daughters of the age group 10-18 years and are conversant in either Marathi, Hindi or English will be included in the study.

Exclusion Criteria

Women with no children or with daughters outside the 10-18 yrs age group have been excluded.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Tata Memorial Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Tata Memorial Hospital

Principal Investigators

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Sharmila A Pimple, MD

Role: PRINCIPAL_INVESTIGATOR

Tata Memorial Hospital

Gauravi A Mishra, MD

Role: PRINCIPAL_INVESTIGATOR

Tata Memorial Hospital

Locations

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Tata Memorial Hospital

Mumbai, Maharashtra, India

Site Status RECRUITING

Countries

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India

Central Contacts

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Sharmila A Pimple, MD

Role: CONTACT

+91-22-24154379

Gauravi A Mishra, MD

Role: CONTACT

+91-22-24157532

Facility Contacts

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Sharmila A Pimple, MD

Role: primary

+91-22-24154379

Gauravi A Mishra, MD

Role: backup

+91-22-24157532

Other Identifiers

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655

Identifier Type: -

Identifier Source: org_study_id