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The Psychological Treatment of Overweight Binge Eaters Minority Supplement

NCT ID: NCT01208259

Last Updated: 2010-09-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1/PHASE2

Total Enrollment

162 participants

Study Classification

INTERVENTIONAL

Study Start Date

1997-04-30

Study Completion Date

1999-03-31

Brief Summary

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Cognitive-behavioral therapy (CBT) has documented efficacy for the treatment of binge eating disorder (BED). Interpersonal psychotherapy (IPT) has been shown to reduce binge eating but its long-term impact and time course on other BED-related symptoms remain largely unknown. This study compares the effects of group CBT and group IPT across BED-related symptoms among overweight individuals with BED.

Detailed Description

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Cognitive-behavioral therapy (CBT) has documented efficacy for the treatment of binge eating disorder (BED). Interpersonal psychotherapy (IPT) has been shown to reduce binge eating but its long-term impact and time course on other BED-related symptoms remain largely unknown. This study compares the effects of group CBT and group IPT across BED-related symptoms among overweight individuals with BED. METHODS: One hundred sixty-two overweight patients meeting DSM-IV criteria for BED were randomly assigned to 20 weekly sessions of either group CBT or group IPT. Assessments of binge eating and associated eating disorder psychopathology, general psychological functioning, and weight occurred before treatment, at posttreatment, and at 4-month intervals up to 12 months following treatment. RESULTS: Binge-eating recovery rates were equivalent for CBT and IPT at posttreatment (64 \[79%\] of 81 vs 59 \[73%\] of 81) and at 1-year follow-up (48 \[59%\] of 81 vs 50 \[62%\] of 81). Binge eating increased slightly through follow-up but remained significantly below pretreatment levels. Across treatments, patients had similar significant reductions in associated eating disorders and psychiatric symptoms and maintenance of gains through follow-up. Dietary restraint decreased more quickly in CBT but IPT had equivalent levels by later follow-ups. Patients' relative weight decreased significantly but only slightly, with the greatest reduction among patients sustaining recovery from binge eating from posttreatment to 1-year follow-up. CONCLUSIONS: Group IPT is a viable alternative to group CBT for the treatment of overweight patients with BED. Although lacking a nonspecific control condition limits conclusions about treatment specificity, both treatments showed initial and long-term efficacy for the core and related symptoms of BED.

Conditions

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Binge Eating Disorder Cognitive Therapy/Methods Mental Disorders/Epidemiology Obesity/Epidemiology Obesity/Therapy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Binge Eating Disorder/Therapy

Group Type EXPERIMENTAL

Cognitive Behavioral Therapy (CBT)

Intervention Type BEHAVIORAL

Interpersonal Therapy (IPT)

Intervention Type BEHAVIORAL

Interventions

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Cognitive Behavioral Therapy (CBT)

Intervention Type BEHAVIORAL

Interpersonal Therapy (IPT)

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* DSM-IV research criteria for binge-eating disorder
* Average of greater than or equal to 2 days of binge eating per week for at least 6 months' duration
* Marked stress regarding binge eating
* At least 3 to 5 associated behavioral features (e.g. eating when not physically hungry) Other study criteria
* 18-65 years old
* Body mass index, 27-48 kg/m squared

Exclusion Criteria

* Pregnant or planning to become pregnant
* Taking weight-affecting or psychotropic medications
* Psychiatric conditions warranting immediate treatment
* Current enrollment in psychotherapy or a weight loss program
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Washington University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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San Diego State University

Principal Investigators

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Denise E Wilfley, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Washington University School of Medicine

Locations

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Yale University

New Haven, Connecticut, United States

Site Status

Countries

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United States

References

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Wilfley DE, Welch RR, Stein RI, Spurrell EB, Cohen LR, Saelens BE, Dounchis JZ, Frank MA, Wiseman CV, Matt GE. A randomized comparison of group cognitive-behavioral therapy and group interpersonal psychotherapy for the treatment of overweight individuals with binge-eating disorder. Arch Gen Psychiatry. 2002 Aug;59(8):713-21. doi: 10.1001/archpsyc.59.8.713.

Reference Type RESULT
PMID: 12150647 (View on PubMed)

Other Identifiers

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R29MH138403

Identifier Type: -

Identifier Source: org_study_id