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Effect of Ambient Light on the Parameters of the Pupillary Light Reflex

NCT ID: NCT01207817

Last Updated: 2010-09-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-09-30

Study Completion Date

2010-02-28

Brief Summary

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The purpose of this study is to determine the effects of varying luminescent levels on the pupillary response.

Detailed Description

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Evaluation of the pupillary response is an underemphasized aspect of the assessment of visual function. The pupillary light reflex is one of the few objective indicators of afferent input from the retina and optic nerve. Since the pupillary light reflex is processed through the retina, it may be used to assess visual integrity (1). Pupillometry is a reliable technology capable of providing repetitive data on quantitative pupillary function in states of health and disease (2). Amplitude, latency, maximum constriction velocity, mean constriction velocity, and dilation velocity are measured using the Neuroleptics pupillometer. The effects of varying levels of ambient light on these parameters of the pupillary response have not been extensively studied. The purpose of this investigation is to determine the effects of varying luminescent levels on the pupillary response.

Conditions

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Healthy Volunteers

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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no condition

no condition - healthy volunteers

Pupillometry

Intervention Type OTHER

Pupillometry readings will be taken at low, intermediate and high ambient light

Interventions

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Pupillometry

Pupillometry readings will be taken at low, intermediate and high ambient light

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* healthy volunteers

Exclusion Criteria

* recent bout of conjunctivitis or infection in the eye recent eye surgery seizure disorder unable to lie flat for 30 minutes known history of eye disease which cannot be corrected with lenses
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Medicine and Dentistry of New Jersey

OTHER

Sponsor Role lead

Responsible Party

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UMDNJ

Principal Investigators

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Lawrence W Chinn, MD

Role: PRINCIPAL_INVESTIGATOR

UMDNJ-NJMS

Locations

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UMDNJ-University Hospital

Newark, New Jersey, United States

Site Status

Countries

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United States

Other Identifiers

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0120090181

Identifier Type: -

Identifier Source: org_study_id