Dose Ranging Study of SPL7013 Gel for Treatment of Bacterial Vaginosis (BV)

NCT ID: NCT01201057

Last Updated: 2019-06-06

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

132 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-08-31

Study Completion Date

2011-05-31

Brief Summary

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The purpose of this study is to determine the efficacy of SPL7013 Gel in the treatment of bacterial vaginosis.

Detailed Description

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Conditions

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Bacterial Vaginosis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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0.5% SPL7013 Gel

Group Type EXPERIMENTAL

0.5% SPL7013 Gel

Intervention Type DRUG

Vaginal gel

1.0% SPL7013 Gel

Group Type EXPERIMENTAL

1.0% SPL7013 Gel

Intervention Type DRUG

Vaginal gel

3.0% SPL7013 Gel

Group Type EXPERIMENTAL

3.0% SPL7013 Gel

Intervention Type DRUG

Vaginal gel

Placebo Gel

Group Type PLACEBO_COMPARATOR

Placebo Gel

Intervention Type OTHER

Vaginal gel

Interventions

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0.5% SPL7013 Gel

Vaginal gel

Intervention Type DRUG

1.0% SPL7013 Gel

Vaginal gel

Intervention Type DRUG

3.0% SPL7013 Gel

Vaginal gel

Intervention Type DRUG

Placebo Gel

Vaginal gel

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Women aged 18-45 years with a diagnosis of BV according to Amsel's criteria and a Nugent score of ≥4
* Otherwise healthy

Exclusion Criteria

* No active STIs
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Starpharma Pty Ltd

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Anne Macek, MD

Role: PRINCIPAL_INVESTIGATOR

contracted to Starpharma Pty Ltd

Locations

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Precision Trials

Phoenix, Arizona, United States

Site Status

Downtown Women's Health Care

Denver, Colorado, United States

Site Status

Clinical Research Center of Nevada

Las Vegas, Nevada, United States

Site Status

Bexar Clinical Trials, LLC

Irving, Texas, United States

Site Status

Tidewater Clinical Research Inc

Virginia Beach, Virginia, United States

Site Status

Countries

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United States

Other Identifiers

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SPL7013-013

Identifier Type: -

Identifier Source: org_study_id

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