Effects of Home-based Pulmonary Rehabilitation in Patients With Severe or Very Severe Chronic Obstructive Pulmonary Disease (COPD)

NCT ID: NCT01198288

Last Updated: 2012-01-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE3

Total Enrollment

182 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-09-30

Study Completion Date

2012-09-30

Brief Summary

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This study will investigate if adding a domiciliary respiratory physiotherapy treatment to standard care in patients with chronic obstructive pulmonary disease (COPD) can improve physical function (walking test) and quality of life.

Detailed Description

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Conditions

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Chronic Obstructive Pulmonary Disease

Keywords

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COPD Respiratory Physiotherapy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Standard Care

Drugs for COPD (as prescribed), oxygen therapy if needed\*, check-up by the general practitioner and/or respirologist as usual.

Educational leaflet regarding optimization of oxygen therapy and drugs; Benefits of physical activity and proposal of a programme of exercise training; Energy conservation techniques; Nutritional counselling; Activity of daily Living (ADL) diary; Prevention and management of acute exacerbation

Monthly phone call with the aim of verifying:

* the patients' clinical conditions;
* the patient's adherence to the pharmacological treatments prescribed
* the patient's compliance in filling out the clinical diary and the ADL diary

Group Type ACTIVE_COMPARATOR

Standard Care

Intervention Type OTHER

As describe in the standard care arm

domiciliary rehabilitation

Same as the standard care group plus 10 (ten) home-based visits supervised by a specifically trained respiratory therapist (education+exercise training) Autonomous home-based programme: The patients will be given instructions and training in order to continue the exercise training programme on the days the respiratory therapist is not visiting them.

Counselling addressed at the outdoor activities.

Group Type EXPERIMENTAL

domiciliary rehabilitation

Intervention Type OTHER

a respiratory rehabilitation programme at the patient home

Interventions

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domiciliary rehabilitation

a respiratory rehabilitation programme at the patient home

Intervention Type OTHER

Standard Care

As describe in the standard care arm

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Severe COPD (FEV1/FVC \< 70% and FEV1 \< 50% pred.) associated to hypoxaemic chronic respiratory insufficiency (PaO2 \< 60mmHg) or
* Very severe COPD (FEV1/FVC \< 70% and FEV1 \< 30% pred.)

With the following characteristics:

* no signs of lung restriction (TLC≥80%)
* clinically stable for at least the last four weeks
* MRC ≥ 2
* no participation to PR programmes in the last year

FEV1= Forced expiratory volume in the 1st second FVC= Forced vital capacity TLC= Total Lung Capacity PaO2= Partial pressure of arterial oxygen

Exclusion Criteria

* \- Muscular-skeletal impairment that could limit the patient's participation to the exercise programme;
* Cognitive impairment that could limit the patient's participation to the activities of education and exercise, as assessed by the Mini Mental State (MMS) test \<26;
* Malignancies
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Associazione Riabilitatori Insufficienza Respiratoria

OTHER

Sponsor Role lead

Responsible Party

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Marta Lazzeri

Dr

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Unità di pneunologia, Ospedale di Busto Arsizio

Busto Arsizio, Varese, Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Marta Lazzeri

Role: CONTACT

Email: [email protected]

Other Identifiers

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01

Identifier Type: -

Identifier Source: org_study_id