Evaluation of Coblation Channeling in Treating Chronic Tonsillitis
NCT ID: NCT01193790
Last Updated: 2010-09-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE2
60 participants
INTERVENTIONAL
2011-01-31
Brief Summary
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Detailed Description
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Bacteria within biofilms are resistant to host defenses and antibiotics. The presence of bacterial biofilms within the tissue and crypts of inflamed tonsils may explain the chronicity and recurrent characteristics of some forms of tonsillitis. There is strong anatomical evidence for the presence of bacterial biofilms in chronically diseased tonsils.
Our hypothesis was that treatment of the crypts and tonsillar tissue may decrease the possible antigen-immune system interaction and inflammation.
The combination of the radio frequency energy and the fluid creates a "plasma" field containing highly ionized particles. The ionized particles have sufficient energy to break organic molecular bonds that can remove tissue selectively without excessive heat production and damage the surrounding tissue. Employing this new technique, the investigators will try to eliminate the cause for chronic tonsillitis.
The combination of the radio frequency energy and the fluid creates a "plasma" field containing highly ionized particles. The ionized particles have sufficient energy to break organic molecular bonds that can remove tissue selectively without excessive heat production and damage the surrounding tissue. Employing this new technique, the investigators will try to eliminate the cause for chronic tonsillitis.
Our hypothesis was that treatment of the crypts and tonsillar tissue may decrease the possible antigen-immune system interaction and inflammation.
Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Coblation
Coblation channeling
The combination of the energy and the fluid creates a "plasma" field containing highly ionized particles (coblation). The ionized particles have sufficient energy to break organic molecular bonds that can remove tissue selectively without excessive heat production and subsequent damage to the surrounding tissue. Treatment of the tonsillar crypts and tissue by coblation may decrease antigen and immune system interaction and inflammation.
Interventions
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Coblation channeling
The combination of the energy and the fluid creates a "plasma" field containing highly ionized particles (coblation). The ionized particles have sufficient energy to break organic molecular bonds that can remove tissue selectively without excessive heat production and subsequent damage to the surrounding tissue. Treatment of the tonsillar crypts and tissue by coblation may decrease antigen and immune system interaction and inflammation.
Eligibility Criteria
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Inclusion Criteria
* suffering from recurrent or chronic sore throat.
* suffering from irregular tonsils with crypts, slight redness or enlargement.
Exclusion Criteria
* allergic to the type of medication included in the study.
* suffering from gastrointestinal (GI) reflux or chronic הפרשה הוסטנזלית
* contraindication to medical or surgical treatment.
* suffering from peritonsillar abscess.
14 Years
70 Years
ALL
No
Sponsors
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Hillel Yaffe Medical Center
OTHER_GOV
Responsible Party
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Hillel Yaffe MC, Hadera, Israel
Locations
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Hillel Yaffe MC,
Hadera, , Israel
Countries
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Facility Contacts
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Other Identifiers
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43-2001
Identifier Type: -
Identifier Source: org_study_id