Visual Outcomes After Bilateral Surgical Cataract Phacoemulsification: AcrySof Toric IOL Implantation Compared to Monofocal IOL Implantation

NCT ID: NCT01192321

Last Updated: 2012-10-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE4

Total Enrollment

9 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-06-30

Study Completion Date

2010-12-31

Brief Summary

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The objectives of this study are to assess and compare bilateral uncorrected distance visual acuity and distance spectacle independence post bilateral implantation of AcrySof Toric Intraocular Lenses (IOLs) and monofocal IOLs. Secondary outcomes will include cost of eyeglass purchased and patient vision-related quality of life.

Detailed Description

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Conditions

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Cataract

Keywords

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intraocular lens Toric

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Toric T3 - T9

Bilateral implantation of a Toric intraocular lens (IOL) models T3, T4, T5, T6, T7, T8 or T9

Group Type EXPERIMENTAL

Toric T3 - T9

Intervention Type DEVICE

Bilateral implantation of Alcon AcrySof Toric Intraocular Lens (IOL) models SN60T3 through SN60T9 following cataract removal.

Monofocal

Bilateral implantation of a monofocal intraocular lens (IOL) model with no toric component.

Group Type ACTIVE_COMPARATOR

Monofocal

Intervention Type DEVICE

Bilateral implantation of any monofocal Intraocular Lens (IOL) following cataract removal.

Interventions

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Toric T3 - T9

Bilateral implantation of Alcon AcrySof Toric Intraocular Lens (IOL) models SN60T3 through SN60T9 following cataract removal.

Intervention Type DEVICE

Monofocal

Bilateral implantation of any monofocal Intraocular Lens (IOL) following cataract removal.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* are willing and able to understand and sign an informed consent;
* are willing and able to attend postoperative examinations per protocol schedule;
* are ≥ 21 years of age, of either gender and any race;
* have bilateral, age related, cataracts;
* have planned cataract removal via phacoemulsification with implantation of an intraocular lens (IOL);
* are available to undergo second eye surgery within 6 weeks of the first eye surgery;
* are in good ocular health, with the exception of cataracts;
* are free of disease(s)/condition(s) listed in the "Precautions" section of the AcrySof Toric and monofocal package inserts: choroidal hemorrhage, chronic severe uveitis, concomitant severe eye disease, extremely shallow anterior chamber, medically uncontrolled glaucoma, microphthalmos, non-age-related cataract, proliferative diabetic retinopathy (severe), severe corneal dystrophy, severe optic nerve atrophy, irregular corneal astigmatism and color vision deficiencies.
* have regular corneal astigmatism;
* qualify for bilateral AcrySof Toric IOLs on the AcrySof Toric Calculator (www.acrysoftoriccalculator.com)
* are able to obtain pupil dilation ≥ 5.0 mm
* are able to read and understand one of the following languages: Dutch, French, German

Exclusion Criteria

* previous corneal surgery and/or reshaping
* abnormality, disease and/or conditions of the cornea (i.e. keratoconus, corneal dystrophy, keratitis, corneal scar, etc.), which would clinically contra-indicate the implantation of a toric intraocular lens
* planned multiple procedures during cataract/IOL implantation surgery
* planned limbal relaxing incision (LRI), Excimer laser treatment or similar procedure prior to or during the course of the study
* an ocular disease and/or condition that may compromise visual acuity levels (i.e. glaucoma, diabetic retinopathy, amblyopia, etc.)
* pregnant, lactating or planning pregnancy during course of study. Subjects who become pregnant during the study will not be discontinued; however, data may be excluded from the effectiveness analyses because pregnancy can alter refraction and visual acuity results. Data will be collected on the CRF as observations.
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alcon Research

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Contact Alcon Call Center for Trial Locations

Paris, , France

Site Status

Countries

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United States France

Other Identifiers

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M09-047

Identifier Type: -

Identifier Source: org_study_id