An Observational Study of the Mean Duration of Trastuzumab (Herceptin) Treatment in Participants With Early or Metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer

NCT ID: NCT01187381

Last Updated: 2017-10-20

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

250 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-04-14

Study Completion Date

2015-10-15

Brief Summary

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This single arm observational study will assess the duration and safety of treatment with trastuzumab in routine clinical practice in participants with early or metastatic HER2-positive breast cancer. Data will be collected from female participants treated with trastuzumab according to the Summary of Product Characteristics and local protocols. Duration of observation for each participant is from therapy initiation until permanent discontinuation for any cause.

Detailed Description

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Conditions

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Breast Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Participants with Breast Cancer

Participants with early or metastatic HER2-positive breast cancer who were receiving treatment with trastuzumab according to local standard of care and in line with the current summary of product characteristics/ local guidelines, will be observed. Dosing and treatment duration of the trastuzumab will be at the discretion of the treating physician.

Trastuzumab

Intervention Type DRUG

Trastuzumab according to local standard of care and in line with the current summary of product characteristics/ local guidelines

Interventions

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Trastuzumab

Trastuzumab according to local standard of care and in line with the current summary of product characteristics/ local guidelines

Intervention Type DRUG

Other Intervention Names

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Herceptin

Eligibility Criteria

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Inclusion Criteria

* HER2-positive breast cancer
* Treated with trastuzumab in accordance with Summary of Product Characteristics and local protocols
* Written informed consent to data collection

Exclusion Criteria

* Any contraindication to trastuzumab
* Clinically relevant cardiovascular disorder or disease
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Hoffmann-La Roche

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Clinical Trials

Role: STUDY_DIRECTOR

Hoffmann-La Roche

Locations

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Cluj Clinical County Hospital; Oncology Dept

Cluj-Napoca, , Romania

Site Status

Countries

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Romania

Other Identifiers

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ML25235

Identifier Type: -

Identifier Source: org_study_id