The Use of Ultrasonic Coagulating Shears Compared to Monopolar Electrocautery in Open Gastric Cancer Surgery

NCT ID: NCT01179750

Last Updated: 2010-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE3

Total Enrollment

256 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-01-31

Study Completion Date

2011-06-30

Brief Summary

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Ultrasonic coagulating shears are made for performing for cutting and hemostasis at once during operation. It was proved that a laparoscopic gastric resection showed significantly shorter operative time and less work load distribution, and more stability of bleeding than before an introduction of ultrasonic coagulating shears .

In an open gastric cancer surgery, ultrasonic coagulating shears have been often used for lymph node dissection or cutting of small vessels in some hospitals in Korea. However its usefulness or effectiveness has not been fully proved. There was only one report about using ultrasonic coagulating shears in open gastrectomy. The report contained small number of subjects and surgical procedures were different from the investigators.

The investigators expect to reduce operative time and blood loss with ultrasonic coagulating shears. Ultrasonic coagulating shears will also enable us to dissect lymph node with closure of lymphatics. This may reduce the amount of drainage fluid from peritoneal cavity and shorten the removal time of a drain, which will also shorten the hospital stay.

The objective of this study is to evaluate the safety and benefit of ultrasonic coagulating shears in open gastrectomy including usefulness and effectiveness by a randomized controlled, prospective study.

Detailed Description

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Conditions

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Stomach Cancer Gastrectomy Ultrasonic Coagulating Shears

Keywords

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Ultrasonic coagulating shears in gastrectomy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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No Ultrasonic Coagulating Shears group

the one arm: operated group without using Ultrasonic coagulation shears during gastrectomy;

Group Type NO_INTERVENTION

No interventions assigned to this group

ultrasonic coagulation shears group

the other arm: operated group using ultrasonic coagulation shears during gastrectomy

Group Type EXPERIMENTAL

Ultrasonic Coagulating Shears

Intervention Type DEVICE

comparison of operated groups between with Ultrasonic Coagulating Shears and without them.

Interventions

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Ultrasonic Coagulating Shears

comparison of operated groups between with Ultrasonic Coagulating Shears and without them.

Intervention Type DEVICE

Other Intervention Names

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Harmonic Ace

Eligibility Criteria

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Inclusion Criteria

* Patients with the diagnosis of gastric cancer
* The patient who agrees to participate in this study by signing the informed consent form

Exclusion Criteria

* The patient who refuse to participate in this study
* Have simultaneously other cancer
* Underwent cancer therapy at past time
* Have bleeding disorder, coagulation disorder, chronic disease (e.g.heart failure, cardiovascular disease, active hepatitis)
* Have a previous upper gastrointestinal surgery
Minimum Eligible Age

20 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Samsung Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Samsung Medical Center, Sungkyunkwan University School of Medicine

Principal Investigators

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Jae Moon Bae, MD., Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Samsung Medical Center, Sungkyunkwan University

Locations

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Samsung Medical Center

Seoul, , South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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Jae Moon Bae, Professor

Role: CONTACT

Phone: +82-2-3410-0252

Email: [email protected]

Facility Contacts

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JaeMoon Bae, MD.,Ph.D.

Role: primary

SeungJong Oh, MD

Role: backup

References

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Tsimoyiannis EC, Jabarin M, Tsimoyiannis JC, Betzios JP, Tsilikatis C, Glantzounis G. Ultrasonically activated shears in extended lymphadenectomy for gastric cancer. World J Surg. 2002 Feb;26(2):158-61. doi: 10.1007/s00268-001-0199-9. Epub 2001 Dec 4.

Reference Type BACKGROUND
PMID: 11865342 (View on PubMed)

Other Identifiers

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2009-08-089

Identifier Type: -

Identifier Source: org_study_id