Intravitreal Bevasizumab Versus Intravitreal Triamcinolone in Central Retinal Vein Occlusion (CRVO)

NCT ID: NCT01178697

Last Updated: 2010-08-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2

Study Classification

INTERVENTIONAL

Study Start Date

2010-01-31

Study Completion Date

2010-12-31

Brief Summary

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This randomized clinical trial is conducted to evaluate the effect of three intravitreal injections of bevasizumab versus two intravitreal injections of triamcinolone in acute central retinal vein occlusion. The outcomes are visual acuity and central macular thickness. The follow-up time is 6 months.

Detailed Description

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Conditions

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Central Retinal Vein Occlusion

Study Design

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Allocation Method

RANDOMIZED

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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Intravitreal triamcinolone

Group Type ACTIVE_COMPARATOR

Triamcinolone Acetonide

Intervention Type DRUG

Intravitreal, 2 mg, 2 times, two months apart.

Intravitreal bevasizumab

Group Type ACTIVE_COMPARATOR

Bevasizumab

Intervention Type DRUG

Intravitreal, 1.25 mg, 3 times, one month apart.

Interventions

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Bevasizumab

Intravitreal, 1.25 mg, 3 times, one month apart.

Intervention Type DRUG

Triamcinolone Acetonide

Intravitreal, 2 mg, 2 times, two months apart.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Recent onset (less than 3 months) central retinal vein occlusion

Exclusion Criteria

* Any previous intervention
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ophthalmic Research Center

AMBIG

Sponsor Role collaborator

Shahid Beheshti University of Medical Sciences

OTHER

Sponsor Role lead

Locations

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Imam Hossein medical center

Tehran, Tehran Province, Iran

Site Status RECRUITING

Countries

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Iran

Facility Contacts

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Alireza Ramezani, Assistant professor

Role: primary

+98 21 22585952

Other Identifiers

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8886

Identifier Type: -

Identifier Source: org_study_id

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