Prophylactic Effects of Ondansetron, Ramosetron, and Palonosetron on Patient-Controlled Analgesia Related Nausea and Vomiting After Urologic Laparoscopic Surgery
NCT ID: NCT01169805
Last Updated: 2011-11-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
105 participants
INTERVENTIONAL
2010-08-31
2011-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
DOUBLE
Study Groups
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ONSERAN
Ondansetron
Ondansetron/single injection/4 mg/IV
NASEA
Ramosetron
Ramosetron HCl/single injection/0.3mg/IV
ALOXI
Palonosetron
Palonosetron HCl/single injection/0.075mg/IV
normal saline
Normal saline inj
normal saline injection 2ml
Interventions
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Ondansetron
Ondansetron/single injection/4 mg/IV
Ramosetron
Ramosetron HCl/single injection/0.3mg/IV
Palonosetron
Palonosetron HCl/single injection/0.075mg/IV
Normal saline inj
normal saline injection 2ml
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Patients aged (20-65 yr) Undergoing Laparoscopic Nephrectomy
* Patients who want a patient-controlled IV analgesia (IV-PCA)
Exclusion Criteria
* History of severe postoperative nausea/vomiting
* Prolonged QT interval on preoperative EKG
* Hypokalemia, Hypomagnesemia
* Intestinal obstruction
* Pregnant female or breast feeding mother
20 Years
65 Years
FEMALE
No
Sponsors
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Yonsei University
OTHER
Responsible Party
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Hae Keum Kil
Professor
Locations
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Severance Hospital, Yonsei University College of Medicine
Seoul, , South Korea
Countries
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Other Identifiers
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4-2010-0176
Identifier Type: -
Identifier Source: org_study_id