Trial Outcomes & Findings for Eliminating Risk of Preventable Adverse Drug Events at the Hospital-community Interface of Care (NCT NCT01164137)

Results Overview

Mean health services utilization 3 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

156 participants

Primary outcome timeframe

3 Months

Results posted on

2013-02-15

Participant Flow

Recruitment period began November 1, 2008 and ended June 30, 2010.

Three participants were excluded from the trail before assignment to groups because they obtained a score of 19 or less on the Mini Mental State Examination (MMSE).

Participant milestones

Participant milestones
Measure	Control: Medication Reconciliation Non-Intervention Medication Reconciliation : Participants not receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.	Experimental: Medication Reconciliation Intervention Medication Reconciliation : Participants receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.
Overall Study STARTED	76	80
Overall Study COMPLETED	76	77
Overall Study NOT COMPLETED	0	3

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Eliminating Risk of Preventable Adverse Drug Events at the Hospital-community Interface of Care

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Experimental: Medication Reconciliation Intervention n=80 Participants Medication Reconciliation : Participants receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.	Control: Medication Reconciliation Non-Intervention n=76 Participants Medication Reconciliation : Participants not receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.	Total n=156 Participants Total of all reporting groups
Age, Categorical <=18 years	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Age, Categorical Between 18 and 65 years	34 Participants n=5 Participants	16 Participants n=7 Participants	50 Participants n=5 Participants
Age, Categorical >=65 years	46 Participants n=5 Participants	60 Participants n=7 Participants	106 Participants n=5 Participants
Age Continuous	68.40 years STANDARD_DEVIATION 14.70 • n=5 Participants	72.59 years STANDARD_DEVIATION 13.27 • n=7 Participants	70.48 years STANDARD_DEVIATION 14.12 • n=5 Participants
Sex: Female, Male Female	41 Participants n=5 Participants	33 Participants n=7 Participants	74 Participants n=5 Participants
Sex: Female, Male Male	39 Participants n=5 Participants	43 Participants n=7 Participants	82 Participants n=5 Participants
Region of Enrollment Canada	80 participants n=5 Participants	76 participants n=7 Participants	156 participants n=5 Participants

PRIMARY outcome

Timeframe: 3 Months

Mean health services utilization 3 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.

Outcome measures

Outcome measures
Measure	Experimental: Medication Reconciliation Intervention n=77 Participants Medication Reconciliation : Participants receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.	Control: Medication Reconciliation Non-Intervention n=76 Participants Medication Reconciliation : Participants not receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.
Health Services Utilization 3 Months Following Hospital Discharge	3.33 Health Services Utilizations Standard Error .35	3.40 Health Services Utilizations Standard Error .29

PRIMARY outcome

Timeframe: 6 Months

Mean health services utilization 6 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.

Outcome measures

Outcome measures
Measure	Experimental: Medication Reconciliation Intervention n=77 Participants Medication Reconciliation : Participants receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.	Control: Medication Reconciliation Non-Intervention n=76 Participants Medication Reconciliation : Participants not receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.
Health Services Utilization 6 Months Following Hospital Discharge	4.57 Health Services Utilizations Standard Error .52	3.93 Health Services Utilizations Standard Error .35

PRIMARY outcome

Timeframe: 9 Months

Mean health services utilization 9 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.

Outcome measures

Outcome measures
Measure	Experimental: Medication Reconciliation Intervention n=77 Participants Medication Reconciliation : Participants receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.	Control: Medication Reconciliation Non-Intervention n=76 Participants Medication Reconciliation : Participants not receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.
Health Services Utilization 9 Months Following Hospital Discharge	5.71 Health Services Utilizations Standard Error .80	4.49 Health Services Utilizations Standard Error .41

PRIMARY outcome

Timeframe: 12 months

Mean health services utilization 12 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.

Outcome measures

Outcome measures
Measure	Experimental: Medication Reconciliation Intervention n=77 Participants Medication Reconciliation : Participants receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.	Control: Medication Reconciliation Non-Intervention n=76 Participants Medication Reconciliation : Participants not receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.
Health Services Utilization 12 Months Following Hospital Discharge	6.74 Health Services Utilizations Standard Error .94	5.03 Health Services Utilizations Standard Error .48

PRIMARY outcome

Timeframe: 18 months

Mean health services utilization 18 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.

Outcome measures

Outcome measures
Measure	Experimental: Medication Reconciliation Intervention n=77 Participants Medication Reconciliation : Participants receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.	Control: Medication Reconciliation Non-Intervention n=76 Participants Medication Reconciliation : Participants not receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.
Health Services Utilization 18 Months Following Hospital Discharge	7.80 Health Services Utilizations Standard Error 1.06	5.95 Health Services Utilizations Standard Error .59

Adverse Events

Experimental: Medication Reconciliation Intervention

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Control: Medication Reconciliation Non-Intervention

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Allan Bailey, M.D.; Study Principal Investigator

Westview Physician Collaborative

Phone: (780)-975-1131

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place