Trial Outcomes & Findings for Repetitive Transcranial Magnetic Stimulation for Treating Depression: A Functional Magnetic Resonance Imaging Study (NCT NCT01162382)
NCT ID: NCT01162382
Last Updated: 2019-02-18
Results Overview
HDRS-24 will be used to measure response to rTMS treatment. A 50% decrease in HDRS-24 score will indicate treatment response; HDRS-24 \< 10 will indicate remission.
TERMINATED
NA
4 participants
At study entry and within 2 days of exiting 4 weeks of rTMS treatment
2019-02-18
Participant Flow
Participant milestones
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Transcranial Magnetic Stimulation
Open-label transcranial magnetic stimulation
Transcranial Magnetic Stimulation: Four 100-second trains and then one 65-second train, with 30-second inter-train intervals, at 1 Hz and 120% of the resting motor threshold will be applied over the right dorsolateral prefrontal cortex. Subsequently, twenty-five 30-second trains, with a 30-second inter-train interval, at 10 Hz and 120% of the resting motor threshold will be applied over the left dorsolateral prefrontal cortex.
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Overall Study
STARTED
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0
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Overall Study
COMPLETED
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0
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Overall Study
NOT COMPLETED
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0
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Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Repetitive Transcranial Magnetic Stimulation for Treating Depression: A Functional Magnetic Resonance Imaging Study
Baseline characteristics by cohort
Baseline data not reported
PRIMARY outcome
Timeframe: At study entry and within 2 days of exiting 4 weeks of rTMS treatmentPopulation: No data are available for this study as the study was terminated and PI has left the institution. Multiple efforts to contact the PI for the relevant data have failed.
HDRS-24 will be used to measure response to rTMS treatment. A 50% decrease in HDRS-24 score will indicate treatment response; HDRS-24 \< 10 will indicate remission.
Outcome measures
Outcome data not reported
SECONDARY outcome
Timeframe: At study entry and within 2 days of exiting 4 weeks of rTMS treatmentPopulation: No data are available for this study as the study was terminated and PI has left the institution. Multiple efforts to contact the PI for the relevant data have failed.
Imaging studies will be compared to determine if any changes in functional connectivity can be correlated with treatment response.
Outcome measures
Outcome data not reported
Adverse Events
Transcranial Magnetic Stimulation
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place