Usefulness of Exhaled NO in the Differential Diagnosis Acute Eosinophilic Pneumonia and Bacterial Pneumonia

NCT ID: NCT01152424

Last Updated: 2011-06-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-07-31

Study Completion Date

2011-12-31

Brief Summary

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Acute eosinophilic pneumonia (AEP) is diagnosed by cell count analysis of bronchoalveolar lavage fluid. However, the performance of bronchoscopy is not easy for patients with AEP, because they usually have hypoxia. Exhaled nitric oxide (FeNO) is usually elevated in the patients with eosinophilic inflammation such as asthma, but there is no previous studies FeNO in the patients with AEP. Investigators hypothesized that FeNO elevated significantly in patients with AEP, and FeNO can be used as non-invasive diagnostic method in patients who are clinically suspected with AEP, especially when the performance of bronchoscopy is difficult.

Detailed Description

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Conditions

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Acute Eosinophilic Pneumonia

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Acute eosinophilic pneumonia

No interventions assigned to this group

Community acquired pneumonia

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* All patients who visited the study hospital with bilateral pneumonic infiltration.

Exclusion Criteria

* Patients who do not agree with our study protocol
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Seoul National University Bundang Hospital

OTHER

Sponsor Role lead

Responsible Party

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Seoul National University Bundang Hospital

Locations

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Armed Forces Capital Hospital

Seongnam, Gyeongi, South Korea

Site Status

Countries

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South Korea

References

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Lee JE, Rhee CK, Lim JH, Lee SM, Shim YS, Lee CT, Won Lee S. Fraction of exhaled nitric oxide in patients with acute eosinophilic pneumonia. Chest. 2012 May;141(5):1267-1272. doi: 10.1378/chest.11-1303. Epub 2011 Oct 20.

Reference Type DERIVED
PMID: 22016484 (View on PubMed)

Other Identifiers

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FeNO in AEP

Identifier Type: -

Identifier Source: org_study_id

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