A Clinical Trial to Compare and Evaluate the Pharmacokinetic Characteristics and the Safety of Fimasartan in Renal Impairment Patients and Healthy Volunteers

NCT ID: NCT01148368

Last Updated: 2012-01-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-06-30

Study Completion Date

2011-07-31

Brief Summary

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The purpose of this study is to compare and evaluate the pharmacokinetic characteristics and the safety of fimasartan in renal impairment patients and healthy volunteers.

Detailed Description

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Conditions

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Renal Impairment

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

NONE

Study Groups

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renal impairment patients

renal impairment patients who eGFR is lower than 30 ml/min/1.73m\^2 without hemodialysis

Group Type EXPERIMENTAL

fimasartan

Intervention Type DRUG

single administration of fimasartan 120mg

healthy volunteers

healthy volunteers group

Group Type ACTIVE_COMPARATOR

fimasartan

Intervention Type DRUG

single administration of fimasartan 120mg

Interventions

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fimasartan

single administration of fimasartan 120mg

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

\<Renal impairment patient\>

* age: 20-65 years
* eGFR: \< 30ml/min/1.73m\^2
* not on dialysis
* body weight: greater than 55kg
* written informed consent

\<Healthy volunteer\>

* age: 20-65 years
* body weight: greater than 55kg
* written informed consent

Exclusion Criteria

* AST, ALT \> 1.5 times of upper normal range
* positive drug or alcohol screening
Minimum Eligible Age

20 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Seoul National University Hospital

OTHER

Sponsor Role collaborator

Boryung Pharmaceutical Co., Ltd

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Yon Su Kim, PhD

Role: PRINCIPAL_INVESTIGATOR

Seoul National University College of Medicine

Locations

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Seoul National University Hospital

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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A657-BR-CT-113

Identifier Type: -

Identifier Source: org_study_id

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