Efficacy of Topiramate for Hospitalized Patients With Alcoholism
NCT ID: NCT01145677
Last Updated: 2011-06-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
PHASE2/PHASE3
90 participants
INTERVENTIONAL
2010-06-30
2011-06-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Topiramate for Hospitalized Patients With Alcoholism: a 12-week Study
NCT01135602
The Effects of Topiramate on Alcohol Use in Alcohol Dependent Subjects
NCT00329407
An Efficacy and Safety Study of Topiramate in the Treatment of Alcohol Dependence
NCT00210925
Effects of Topiramate on Adolescent Alcohol Use: Efficacy and Mechanisms
NCT01641445
Topiramate Treatment of Hazardous and Harmful Alcohol Use in Veterans With TBI
NCT01750268
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Topiramate
Topiramate
Topiramate 100-300 mg/day orally twice per day
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Topiramate
Topiramate 100-300 mg/day orally twice per day
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* DSM-IV-TR alcohol dependence
* for male: history of alcohol drink \>=35/week, female: history of alcohol drink \>=28/week for at least 1 week during four weeks prior to the admission
* AUDIT score at least 8
* mild or no alcohol withdrawal symptom
* BMI \> 18 kg/m2
* not pregnant and no plan for pregnancy
* intention to decrease or stop drinking
Exclusion Criteria
* other substance dependence, except nicotine and caffeine dependence, during 6 months prior to enrollment
* taking antipsychotics, mood stabilizers, anticonvulsants, opioid analgesics, systemic steroids, carbonic anhydrase inhibitors, hydrochlorthiazide, metformin, pioglitazone, or disulfiram
* unstable medical condition
* medical history of narrow angle glaucoma, renal impairment, kidney stones, and seizures
* moderate to high risk of suicide
* under legal process
* plan to receive a formal treatment for alcoholism from other treatment settings
* pregnancy and nursing woman
* abnormal laboratory tests, including blood urea nitrogen, creatinine, electrolytes, and fasting blood sugar
18 Years
60 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Chiang Mai University
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Department of Psychiatry, Faculty of Medicine, Chiang Mai University
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Surinporn Likhitsathian, MD
Role: PRINCIPAL_INVESTIGATOR
Department of Psychiatry, Faculty of Medicine, Chiang Mai University
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Chiang Mai Drug Dependence Treatment Center
Maerim, Chiang Mai, Thailand
Maharaj Nakorn Chiang Mai Hospital
Muang, Chiang Mai, Thailand
Suanprung Psychiatric Hospital
Muang, ChiangMai, Thailand
Maharaj Nakorn Chiang Mai Hospital
Muang, ChiangMai, Thailand
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
THoPA-R
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.