Transversus Abdominis Plane Block From Abdominal Approach
NCT ID: NCT01144273
Last Updated: 2010-06-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
50 participants
INTERVENTIONAL
2010-05-31
2010-10-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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0.5% Ropivacaine
group receiving TAP block (0.5% ropivacaine at TAP plane)
Transversus abdominis plane block
This intraabdominal approach to TAP block is being used regularly by gynaecological surgeons in this hospital now.
To be performed bilaterally before surgical wound closure by an experienced surgeon who initially undergo initial observation by investigator to ensure uniformity in technique.
Local anaesthetic or placebo solution will be injected to TAP with blunt needle from within abdominal cavity under visual and tactile guidance at the triangle of Petit, after feeling one 'pop' through the transversus abdominis muscle to the TAP layer.
After careful aspiration to exclude vascular puncture, 1.5mg/kg of 0.5% ropivacaine or 0.3ml/kg of 0.9% saline placebo will be injected to each side slowly while observing for signs of toxicity.
normal saline
group receiving placebo (saline) at TAP plane
Transversus abdominis plane block
This intraabdominal approach to TAP block is being used regularly by gynaecological surgeons in this hospital now.
To be performed bilaterally before surgical wound closure by an experienced surgeon who initially undergo initial observation by investigator to ensure uniformity in technique.
Local anaesthetic or placebo solution will be injected to TAP with blunt needle from within abdominal cavity under visual and tactile guidance at the triangle of Petit, after feeling one 'pop' through the transversus abdominis muscle to the TAP layer.
After careful aspiration to exclude vascular puncture, 1.5mg/kg of 0.5% ropivacaine or 0.3ml/kg of 0.9% saline placebo will be injected to each side slowly while observing for signs of toxicity.
Interventions
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Transversus abdominis plane block
This intraabdominal approach to TAP block is being used regularly by gynaecological surgeons in this hospital now.
To be performed bilaterally before surgical wound closure by an experienced surgeon who initially undergo initial observation by investigator to ensure uniformity in technique.
Local anaesthetic or placebo solution will be injected to TAP with blunt needle from within abdominal cavity under visual and tactile guidance at the triangle of Petit, after feeling one 'pop' through the transversus abdominis muscle to the TAP layer.
After careful aspiration to exclude vascular puncture, 1.5mg/kg of 0.5% ropivacaine or 0.3ml/kg of 0.9% saline placebo will be injected to each side slowly while observing for signs of toxicity.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Age 18 or above
* Scheduled to undergo TAH+/- salpingoophorectomy.
* Scheduled to receive general anaesthesia under standardized anaesthetic regime.
* Comprehends how to use intravenous patient controlled analgesia (IV PCA).
* Is willing to complete the postoperative assessment.
* Understands the nature and purpose of this study and the study procedures and has signed the informed consent form for this study to indicate this understanding.
Exclusion Criteria
* Previously taking medications thought to result in opioid tolerance, or analgesics thought to interfere with subsequent opioid requirement.
* Undergoing any procedures in addition to TAH+/- salpingoophorectomy.
* With co-existing pathology resulting in persistent pain requiring analgesics.
* Wound incision extending to supra-umbilical level.
18 Years
FEMALE
No
Sponsors
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United Christian Hospital
OTHER
Responsible Party
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United Christian Hospital, Hospital Authority
Principal Investigators
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Wing Yee Lillian Choy, MBBS (HK)
Role: PRINCIPAL_INVESTIGATOR
United Christian Hospital, Hospital Authority
Locations
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Department Of Anaesthesiology, Pain medicine and Operating Services. United Christian Hospital
Kwun Tong, Kowloon, Hong Kong
Countries
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Central Contacts
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Facility Contacts
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Wing Yee Lillian Choy, MBBS (HK)
Role: primary
References
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McDonnell JG, O'Donnell B, Curley G, Heffernan A, Power C, Laffey JG. The analgesic efficacy of transversus abdominis plane block after abdominal surgery: a prospective randomized controlled trial. Anesth Analg. 2007 Jan;104(1):193-7. doi: 10.1213/01.ane.0000250223.49963.0f.
Carney J, McDonnell JG, Ochana A, Bhinder R, Laffey JG. The transversus abdominis plane block provides effective postoperative analgesia in patients undergoing total abdominal hysterectomy. Anesth Analg. 2008 Dec;107(6):2056-60. doi: 10.1213/ane.0b013e3181871313.
Bonnet F, Berger J, Aveline C. Transversus abdominis plane block: what is its role in postoperative analgesia? Br J Anaesth. 2009 Oct;103(4):468-70. doi: 10.1093/bja/aep243. No abstract available.
Other Identifiers
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KC/KE-10-0021/FR-3
Identifier Type: OTHER
Identifier Source: secondary_id
Protocol ver 1.1
Identifier Type: -
Identifier Source: org_study_id