Male Involvement in Antenatal Care and the Prevention Programme of Mother-to-child Transmission of HIV in Uganda

NCT ID: NCT01144234

Last Updated: 2013-01-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

1060 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-06-30

Study Completion Date

2010-12-31

Brief Summary

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HIV /AIDS is a major public health problem in Uganda. The prevention of mother to child transmission of HIV/ AIDS (PMTCT) was launched in Uganda in November 2001 and in Mbale Hospital in May 2002. Currently, PMTCT services have been integrated into mainstream antenatal care services throughout the country.

Though engaging men as partners is a critical component in the PMTCT programme, their involvement has been low. Measures to increase male partner involvement in the PMTCT programmes have not been explored in Uganda.

Objectives: To determine the effect of a written invitation letter to the spouses of women, attending their first antenatal visit on: (a) couple attendance at subsequent antenatal clinic visits; and (b) couple acceptance of HIV testing.

Study site: The study will be carried out at Mbale Regional Referral Hospital in eastern Uganda

Study design: A randomised clinical trial among 1060 (530 intervention and 530 control) new antenatal attendees. The intervention will be a written invitation letter to their spouses.

Outcome measures: The main outcome measure is the proportion of pregnant women who come with their partners for ANC at the subsequent antenatal visit.

Utility: The results of this study will be utilised in re-orienting the ANC services to encourage male participation and hopefully improve the uptake of the PMTCT services at Mbale Regional Referral Hospital.

Detailed Description

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Conditions

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HIV Infection

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Invitation letter to male spouse

In this arm the pregnant women got an invitation letter for the spouse to attend at the next antenatal visit

Group Type EXPERIMENTAL

Invitation letter for male spouse

Intervention Type BEHAVIORAL

In this arm the pregnant women got an invitation letter for the spouse to attend at the next antenatal visit

Information letter

In this arm the pregnant women got an information letter about antenatal care.

Group Type PLACEBO_COMPARATOR

Information letter

Intervention Type BEHAVIORAL

In this arm the pregnant women got an information letter

Interventions

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Invitation letter for male spouse

In this arm the pregnant women got an invitation letter for the spouse to attend at the next antenatal visit

Intervention Type BEHAVIORAL

Information letter

In this arm the pregnant women got an information letter

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* New antenatal mothers (attendees) at Mbale regional referral hospital
* Acceptance to attend at least two subsequent antenatal visits at Mbale hospital

Exclusion Criteria

* Women attending with their spouses at the first ANC visit
* Refusal to take the letter to her spouse
* Women with inaccessible spouses
Minimum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Makerere University

OTHER

Sponsor Role collaborator

Centre For International Health

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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James K Tumwine, MD, PhD

Role: STUDY_CHAIR

Makerere University

Thorkild Tylleskar, MD, PhD

Role: STUDY_CHAIR

Centre for International Health, University of Bergen

Locations

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Mbale Regional Referral Hospital

Mbale, Eastern Region, Uganda

Site Status

Countries

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Uganda

References

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Byamugisha R, Astrom AN, Ndeezi G, Karamagi CA, Tylleskar T, Tumwine JK. Male partner antenatal attendance and HIV testing in eastern Uganda: a randomized facility-based intervention trial. J Int AIDS Soc. 2011 Sep 13;14:43. doi: 10.1186/1758-2652-14-43.

Reference Type RESULT
PMID: 21914207 (View on PubMed)

Byamugisha R, Tumwine JK, Semiyaga N, Tylleskar T. Determinants of male involvement in the prevention of mother-to-child transmission of HIV programme in Eastern Uganda: a cross-sectional survey. Reprod Health. 2010 Jun 23;7:12. doi: 10.1186/1742-4755-7-12.

Reference Type RESULT
PMID: 20573250 (View on PubMed)

Other Identifiers

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InvolvMaleUg

Identifier Type: -

Identifier Source: org_study_id

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