Chlorhexidine Mouthrinses and Plaque Control

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-02-28

Study Completion Date

2007-04-30

Brief Summary

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The aim of the present study was to compare antiplaque effectiveness of two commercial mouthrinses: 0.12 % Chlorhexidine alcohol base (CLX-A) versus a diluted 0.1% Chlorhexidine non-alcohol base with 0.1% of Formaldehyde (CLX-F).

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Detailed Description

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Chlorhexidine (CLX) mouthrinse has been the gold standard as antiplaque solution.However, if its efficiency seems to be preserved even if the chlorhexidine concentration is bellow 0.10%, the formulation of the final product may affect the effectiveness. Thus, it can be concluded from this study that 0.12% CLX alcohol base mouthrinse is significantly more effective in inhibiting plaque than the diluted 0.1% CLX non-alcohol base containing formaldehyde mouthrinse.

Conditions

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Dental Plaque

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Chlorhexidine alcohol-base mouthrinse

Group Type ACTIVE_COMPARATOR

Synthodont

Intervention Type DRUG

15 ml, tree times/day for 07 days

Arm: Chlorhexidine alcohol-base mouthrinse

non alcohol chlorhexidine mouthrinse

Group Type EXPERIMENTAL

Soludent

Intervention Type DRUG

15ml of 01% Chlorhexidine non alcohol-based, 3 times a day for 7 days

Arm: Experimental: non alcohol chlorhexidine mouthrinse

Interventions

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Synthodont

15 ml, tree times/day for 07 days

Arm: Chlorhexidine alcohol-base mouthrinse

Intervention Type DRUG

Soludent

15ml of 01% Chlorhexidine non alcohol-based, 3 times a day for 7 days

Arm: Experimental: non alcohol chlorhexidine mouthrinse

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* give written informed consent before entering the study
* accept to stop tooth cleaning for a week

Exclusion Criteria

* less than 20 teeth;
* presence of periodontal disease
* presence of factors of plaque retention (clinically unacceptable restorations, important carious, dental overlapping, removable prosthesis, faulty fixed prosthesis, orthodontic appliances),
* associated systemic diseases (diabetes, heart disorders, blood diseases, HIV infection),
* use of antibiotics or other anti-inflammatory drugs during the latest months,
* known allergy against components of mouth rinses,
* pregnancy,
* smoking

Minimum Eligible Age

20 Years

Maximum Eligible Age

25 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes