Canthaxanthin Retinopathy: A Long-term Observation

NCT ID: NCT01128062

Last Updated: 2010-05-21

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 35 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 1983-12-31
• Study Completion Date: 2010-05-31

Brief Summary

Canthaxanthine is a naturally occurring carotenoid that has been a popular over-the-counter oral artificial tanning agent in Europe, Canada, and Australia since 1979. It is also used at low dosage as a food-colouring agent and as a therapeutic agent for photosensitivity disorders such as erythropoietic protoporphyria. Canthaxanthin retinopathy was first described in 1982 by Cortin et al. In Germany the office of the federal board of health refused the permit for oral tanning agents containing canthaxanthine in 1985. At that time the long-term course of the disease was not known. 25 years later the investigators did these long-term follow-up examinations.

Conditions

Canthaxanthin Retinopathy

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• patients using oral tanning agents for at least 2 months.
• patients of 18 years or older

Exclusion Criteria

• none.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University of Cologne

OTHER

Sponsor Role: lead

Locations

University Eye Hospital, University of Cologne

Cologne, North Rhine-Westphalia, Germany

Countries

Germany

Other Identifiers

AHARMS-8310

Identifier Type: -

Identifier Source: org_study_id