Association Between the Menstrual Cycle and Weight Loss

NCT ID: NCT01119976

Last Updated: 2012-12-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-01-31

Study Completion Date

2010-08-31

Brief Summary

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This is a research study to look at the association between weight loss and the menstrual cycle in healthy, overweight, premenopausal women. Participants will be asked to follow a reduced-calorie diet and exercise plan for 3 months.

Detailed Description

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Two different reduced calorie diet and exercise plans will be compared. One plan changes diet and exercise prescription with the phases of the menstrual cycle, while the other is a standard reduced calorie diet and exercise plan based on MyPyramid.gov website.

Conditions

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Overweight Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Group A

Reduced calorie diet and exercise plan that changes with phases of the menstrual cycle

Group Type EXPERIMENTAL

Reduced calorie diet and exercise plan

Intervention Type BEHAVIORAL

Participants will receive written diet and exercise instructions to follow for the duration of the study.

Group B

Different reduced calorie diet and exercise plan based on MyPyramid.gov website

Group Type ACTIVE_COMPARATOR

Different reduced calorie diet and exercise plan

Intervention Type BEHAVIORAL

Participants will receive written diet and exercise instructions to follow for the duration of the study.

Interventions

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Reduced calorie diet and exercise plan

Participants will receive written diet and exercise instructions to follow for the duration of the study.

Intervention Type BEHAVIORAL

Different reduced calorie diet and exercise plan

Participants will receive written diet and exercise instructions to follow for the duration of the study.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Healthy females between the ages of 18-40 (inclusive)
* BMI between 26.5-35.4 kg/m² (inclusive)
* Regular menstrual cycle (28 ± 3 days)
* Weight stable (within ± 3-kg) 2 months prior to study inclusion
* Must use barrier contraception (e.g. male/female condom) for the study's duration
* Must be willing to follow the prescribed diet/exercise plan for the study's duration

Exclusion Criteria

* On hormonal contraceptives or any other daily use of medications which can make the subject unsuitable for inclusion in the study.
* Any significant health problem (history of cancer, HIV/AIDS, Diabetes, cardiovascular disease, untreated hypothyroidism, etc.)
* Restrictions against participating in cardiovascular exercise and strength training
* Any condition, which in the opinion of the investigator makes the subject unsuitable for inclusion in the study.
* Women who are pregnant, lactating, or planning to become pregnant during the study period
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Sierra Neuropharmaceuticals

UNKNOWN

Sponsor Role collaborator

University of Colorado, Denver

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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James O Hill, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

University of Colorado Denver and Health Sciences Center

Locations

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Center for Human Nutrition

Denver, Colorado, United States

Site Status

Countries

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United States

Other Identifiers

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09-0983

Identifier Type: -

Identifier Source: org_study_id