Conservative Treatment Versus the Surgical Treatment of Diaphyseal Fractures of Humerus

NCT ID: NCT01116349

Last Updated: 2012-12-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

4 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-01-31

Study Completion Date

2014-07-31

Brief Summary

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The fracture of the humeral diaphysis is a condition that represents 2% of all fractures. The conservative treatment of diaphyseal fractures of the humerus has long been considered the only option and the surgical treatment was primarily reserved for displaced fractures with no contact of bone ends. However, for a few years there has been an upsurge of indications for the surgical treatment of diaphyseal fractures.

The purpose of this study is to compare the functional outcomes and the quality of life of surgically treated patients versus those who undergo a conservative treatment.

Detailed Description

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Conditions

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Humeral Diaphysis Fracture

Keywords

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humeral diaphysis fracture plate and screws for humeral diaphysis fracture nailing for humerus diaphysis fracture Hanging Support System

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Surgical treatment

Patients included in the surgical group will have surgery to treat the fracture.

Group Type ACTIVE_COMPARATOR

Plate and screws or nailing

Intervention Type PROCEDURE

Patients included in the surgical group will be divided into two subgroups according to the method of fixation chosen: plate and screws or nailing. Surgeries take place under general anesthesia and a prophylaxis antibiotic is administrated. The installation and the approach will be chosen by the surgeon according to his preferences. A thoraco brachial brace is placed on the patient at the end of the intervention and it remains in place for a period of 5 to 10 days (patient comfort). A gradual mobilization of the elbow and shoulder will be initiated by the patient at home. The addition of physical therapy will be decided by the surgeon and noted down accordingly.

Conservative treatment group

Patients included in the conservative group will be taken to a plaster room where a Hanging Support System(HSS) brace will be installed by a qualified technician.

Group Type ACTIVE_COMPARATOR

Hanging Support System (HSS) brace

Intervention Type DEVICE

Patients included in the conservative group will be taken to a plaster room where the HSS brace will be installed by a qualified technician. Advice will be provided for the care, personal hygiene and clothing. The brace will be kept for a period of 6 to 12 weeks depending on the degree of healing of fracture. The maintenance of the proximal part (Brace) may be recommended by the surgeon. The mobilization will begin with exercises at home and whether the patient does physical therapy or not is the surgeon's choice.

Interventions

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Plate and screws or nailing

Patients included in the surgical group will be divided into two subgroups according to the method of fixation chosen: plate and screws or nailing. Surgeries take place under general anesthesia and a prophylaxis antibiotic is administrated. The installation and the approach will be chosen by the surgeon according to his preferences. A thoraco brachial brace is placed on the patient at the end of the intervention and it remains in place for a period of 5 to 10 days (patient comfort). A gradual mobilization of the elbow and shoulder will be initiated by the patient at home. The addition of physical therapy will be decided by the surgeon and noted down accordingly.

Intervention Type PROCEDURE

Hanging Support System (HSS) brace

Patients included in the conservative group will be taken to a plaster room where the HSS brace will be installed by a qualified technician. Advice will be provided for the care, personal hygiene and clothing. The brace will be kept for a period of 6 to 12 weeks depending on the degree of healing of fracture. The maintenance of the proximal part (Brace) may be recommended by the surgeon. The mobilization will begin with exercises at home and whether the patient does physical therapy or not is the surgeon's choice.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Male or female over 18 years
* Fracture of the humeral diaphysis
* Recent fracture (14 days or less)
* Closed fracture
* Signing of consent form

Exclusion Criteria

* Segmental fracture of the humerus
* Fracture with proximal or distal intra articular extension
* Open fracture
* Polytrauma
* Floating elbow or shoulder
* Pathological fracture
* Simultaneous fracture of both humerus
* Associated vascular disease
* Severe neuromuscular disorders such as Parkinson, hemiparesis, myasthenia gravis, muscular dystrophy, etc. ...
* medical contraindication to surgery
* severe central neurological disease disabling patient to fill in questionnaires (senile dementia, Alzheimer's, etc ...
* Male or female unable to consent
* Any other condition which prevents the assessor from fully monitoring the patient during study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hopital de l'Enfant-Jesus

OTHER

Sponsor Role lead

Responsible Party

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Pelet Stephane

Dr Stephane Pelet MD, PhD Orthopedic surgeon

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Stéphane Pelet, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Hôpital de l'Enfant-Jésus

Locations

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CHA-Pavillon Enfant-Jésus

Québec, Quebec, Canada

Site Status

Hôpital l'Enfant-Jésus

Québec, Quebec, Canada

Site Status

Countries

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Canada

Other Identifiers

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PEJ-530

Identifier Type: -

Identifier Source: org_study_id