Screening for Fabry Disease Among Young Stroke Patients in an Israeli Stroke Clinic

NCT ID: NCT01109875

Last Updated: 2014-06-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

1000 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-05-31

Brief Summary

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The purpose of this study is to determine the incidence of Fabry Disease in young stroke patients in an Israeli stroke clinic.

Detailed Description

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Conditions

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Fabry Disease in the Young Stroke

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Interventions

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blood test

Dry blood spots (DBS) analysis of a- galactosidase-A activity will be used for male patients' diagnosis. Males and females with enzymatic activity bellow the test's cut-off will be further diagnosed by gene sequencing. Since females are heterozygote and may have high residual levels of active enzyme, female patients with a- galactosidase-A activity of 30% bellow averaged normal range will also be further diagnosed by gene sequencing as described before (8).

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

diagnosis of stoke or TIA Time period within last 5 years -

Exclusion Criteria

Known diagnosis of stroke or index event due to trauma

\-
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Wolfson Medical Center

OTHER_GOV

Sponsor Role lead

Responsible Party

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Dr. Yair Lampl

Professor Yair Lampl

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Neurology Dept. Edith Wolfson Medical Center

Holon, , Israel

Site Status

Countries

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Israel

Other Identifiers

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1

Identifier Type: -

Identifier Source: org_study_id

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