Clinical Evaluation of 0.1% Olopatadine Hydrochloride Ophthalmic Solution in Pediatric Patients

NCT ID: NCT01109485

Last Updated: 2015-05-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

42 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-03-31

Study Completion Date

2011-07-31

Brief Summary

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The objective of this study is to further evaluate the safety of Olopatadine Ophthalmic Solution 0.1% in Japanese children with allergic conjunctivitis.

Detailed Description

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Conditions

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Allergic Conjunctivitis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Olopatadine

Olopatadine hydrochloride ophthalmic solution 0.1%

Group Type EXPERIMENTAL

Olopatadine hydrochloride ophthalmic solution 0.1%

Intervention Type DRUG

1-2 drops 4 times per day

Interventions

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Olopatadine hydrochloride ophthalmic solution 0.1%

1-2 drops 4 times per day

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients whose parents or guardians can issue informed consent
* Patients aged over 7 and less than 16 at the baseline
* Patients confirmed to show type I allergy
* Patients with allergic conjunctivitis
* Patients having subjective symptoms at the baseline (itching sensation, foreign body sensation, eye pain, etc.)

Exclusion Criteria

* Patients having ocular itching sensation and injection caused by disease other than allergic conjunctivitis
* Patients having retinal detachment, diabetic retinopathy or progressive retinal disease
* Patients with a history of ocular infection, corneal herpes or relapsing corneal erosion of sudden onset or secondary to corneal injury
* Patients having received continuous treatment with corticosteroid within 3 months
* Patients having received immunotherapy
* Patients requiring continuous treatment of corticosteroid, immunosuppressors, non-steroidal anti-inflammatory agents, vasoconstrictors, anti-histamines, anti-allergy agents, herbal preparations indicated for "conjunctivitis" or any ophthalmic solution other than the test product
* Patients having undergone ocular laser therapy within 3 months
* Unilaterally blind patients (best corrected visual acuity: below 0.01)
* Patients with a history of allergy or hypersensitivity to olopatadine hydrochloride
* Patients necessitating the use of contact lens during the study period
* Other patients judged by the attending physician as inappropriate for study
Minimum Eligible Age

7 Years

Maximum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alcon Research

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Eriko Chono

Role: STUDY_DIRECTOR

Alcon Research

Locations

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Contact Alcon Call Center For Trial Locations

Tokyo, , Japan

Site Status

Countries

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Japan

Other Identifiers

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JPN-P-2010-1

Identifier Type: -

Identifier Source: org_study_id

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