Evaluation of Dose-effect of a New Fermented Food in Healthy Adults

NCT ID: NCT01108419

Last Updated: 2020-12-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

96 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-03-31

Study Completion Date

2012-06-30

Brief Summary

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The aim of the study is to assess the safety and tolerance of a new fermented food versus a control product in healthy adults during the 4-week consumption period.

Detailed Description

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Conditions

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Healthy

Keywords

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healthy adults

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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1 = Test Product normal dose

Fermented dairy product containing probiotics - normal dose

Group Type ACTIVE_COMPARATOR

Fermented dairy product

Intervention Type OTHER

2 = Test Product high dose

Fermented dairy product containing probiotics - high dose

Group Type ACTIVE_COMPARATOR

Fermented dairy product

Intervention Type OTHER

3 = Control Product normal dose

Non-fermented dairy product - normal dose

Group Type SHAM_COMPARATOR

milk-based non-fermented dairy product

Intervention Type OTHER

4 = Control Product high dose

Non-fermented dairy product - high dose

Group Type SHAM_COMPARATOR

milk-based non-fermented dairy product

Intervention Type OTHER

Interventions

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Fermented dairy product

Intervention Type OTHER

milk-based non-fermented dairy product

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Subjects after receiving a full description of the study, provide written informed consent to take part in the study.
* Free-living subject, as evaluated during the clinical examination.
* Male/female subjects aged between 18 to 55 years (bounds included).
* Subjects with a body mass index (BMI) between 18.5 ≤ BMI \< 30kg/m².
* Healthy subjects (as determined by a medical examination)

Exclusion Criteria

* Subjects with any allergy (food, respiratory…).
* Subjects that have had any surgery or intervention requiring general anaesthesia in the last 4 weeks.
* Subjects with a history of chronic metabolic or gastrointestinal disease with the exception of appendectomy.
* Subjects with chronic or iatrogenic immunodeficiency (e.g. Chemotherapy, HIV).
* Subjects presenting a severe evolutive or chronic pathology (e.g. cancer,tuberculosis, Crohn's disease, cirrhosis, multiple sclerosis, Type I diabetes…).
* Subject with eating disorders.
* Subjects with cardiac, respiratory (including asthma) or renal insufficiency, cardiomyopathy, valvulopathy and medical history of rheumatic fever.
* Subjects with special medicated diet (for obesity, anorexia, metabolic pathology…).
* For female subjects: pregnancy, breast-feeding or not willing to use/not using an acceptable method of contraception
* Subject, in the Investigator's opinion, should not be randomised.
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Danone Global Research & Innovation Center

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Harrison Clinical Research Clinical Unit, Hilblestrasse 54

München, , Germany

Site Status

Countries

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Germany

Other Identifiers

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NU327

Identifier Type: -

Identifier Source: org_study_id