Integrated Whole-Genome Analysis of Hematologic Disorders

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

35 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-09-30

Study Completion Date

2013-08-02

Brief Summary

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We will use new technologies to look at the DNA, RNA, proteins, and metabolites in the disease-containing blood, bone marrow, or tissue and normal cells from the skin. Our goal is to analyze all of the genes in the diseased and normal skin sample. By comparing the results of the diseased sample and normal skin cells and the results of the two types of genetic information (DNA and RNA), we should be able to identify genetic changes that are important for the initiation, progression, or treatment response of that particular disorder.

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Detailed Description

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Conditions

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Hematologic Diseases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Blood Draw

Intervention Type PROCEDURE

Skin Biopsy

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. 18 years of age or older
2. Patient meets the clinical and/or pathologic criteria for the hematologic disorder being examined.
3. Patient is willing to provide a skin biopsy and five 10 mL tubes of peripheral blood.