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Postoperative Cognitive Dysfunction After Total Knee or Hip Replacement Surgery in Fast-track Set-up

NCT ID: NCT01103752

Last Updated: 2011-12-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

225 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-10-31

Study Completion Date

2011-12-31

Brief Summary

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The aim of this study is to quantify the incidence of postoperative cognitive dysfunction in the elderly patient (\>60y) after total hip or knee replacement surgery. The hypothesis is that the fast-track methodology with a mean hospital stay less than 3 days will help to minimize this reduction in memory and concentration.

Detailed Description

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Conditions

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Postoperative Cognitive Dysfunction

Study Design

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Study Time Perspective

PROSPECTIVE

Study Groups

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Surgery

This group (n=220) consist of patients undergoing hip or knee replacement in a fast-track setup and they are tested 3 times for postoperative cognitive dysfunction.

no intervention, descriptive study

Intervention Type OTHER

no intervention, descriptive study

Interventions

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no intervention, descriptive study

no intervention, descriptive study

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 60 years of age or above
* ASA classification 1-4
* undergoing fast-track hip or knee replacement

Exclusion Criteria

* anaesthesia within the past 90 days
* daily consumption of sleep or anxiety medication
* more than 35 units of alcohol per week
* lack of proper verbal and reading skills, Danish
* Serious hearing or visual impairment
* Mini mental status evaluation (MMSE) \< 24
* Parkinsons Disease or other neurological disease causing functional impairment
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Lundbeck Foundation

OTHER

Sponsor Role collaborator

Lene Krenk

OTHER

Sponsor Role lead

Responsible Party

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Lene Krenk

MD

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Lene Krenk, Doctor

Role: PRINCIPAL_INVESTIGATOR

Rigshospitalet, Denmark

Locations

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The Lundbeck Centre for fast-track hip/knee surgery

Copenhagen, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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H-3-2009-096

Identifier Type: -

Identifier Source: org_study_id