Evaluation Of Striatal Glucose Metabolism With Positron Emission Tomography Following PF-02545920 In Healthy Subjects
NCT ID: NCT01103726
Last Updated: 2011-11-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1
34 participants
INTERVENTIONAL
2010-05-31
2011-11-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
TRIPLE
Study Groups
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Stage 1
PF-02545920
1 and 5 mg tablets, 6 mg single dose
placebo
matching placebo tablets, single dose
Stage 2
PF-02545920
1 mg tablets, 3 mg single dose
PF-02545920
5 mg tablets, 15 mg single dose
Placebo
matching placebo tablets, single dose
Interventions
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PF-02545920
1 and 5 mg tablets, 6 mg single dose
placebo
matching placebo tablets, single dose
PF-02545920
1 mg tablets, 3 mg single dose
PF-02545920
5 mg tablets, 15 mg single dose
Placebo
matching placebo tablets, single dose
Eligibility Criteria
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Inclusion Criteria
* Body Mass Index (BMI) of 17.5 to 30.5 kg/m2; and a total body weight \>50 kg (110 lbs)
* An informed consent document signed and dated by the subject
* Subjects who are willing and able to comply with scheduled visits, treatment plan, laboratory tests, and other study procedures
Exclusion Criteria
* History of agranulocytosis or movement disorder
* Positron Emission Tomography (PET) or Magnetic Resonance Imaging (MRI) contraindications
18 Years
55 Years
ALL
Yes
Sponsors
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Yale University
OTHER
Pfizer
INDUSTRY
Responsible Party
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Principal Investigators
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Pfizer CT.gov Call Center
Role: STUDY_DIRECTOR
Pfizer
Locations
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Pfizer Investigational Site
New Haven, Connecticut, United States
Pfizer Investigational Site
New Haven, Connecticut, United States
Pfizer Investigational Site
New Haven, Connecticut, United States
Countries
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Related Links
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Other Identifiers
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A8241013
Identifier Type: -
Identifier Source: org_study_id