Effect of Early Rest on Recovery From Pediatric Concussion

NCT ID: NCT01101724

Last Updated: 2013-11-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

99 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-04-30

Study Completion Date

2012-12-31

Brief Summary

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The purpose of this study is to find out if strict rest for 5 days helps children get better after concussion.

Detailed Description

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The purpose of this study is to find out if strict rest for 5 days helps children get better after concussion. This research is being done because, currently, there is no effective treatment for concussion. Physical activity (for example; running, playing sports) and brain activity (for example; homework and tests) may make concussion symptoms worse. We are studying whether strict rest after concussion may help improve symptoms. About 110 children, ages 11-22 years old will take part in this study at the Children's Hospital of Wisconsin. This study is being funded by the Injury Research Center. The research grant pays for study procedures, follow-up testing, and patient reimbursement. Research staff is not being provided incentives to enroll subjects.

Conditions

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Mild Traumatic Brain Injury Concussion Post-concussive Syndrome

Keywords

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mild traumatic brain injury Concussion postconcussive syndrome

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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Standard of Care

In this group, the treating attending physician will be free to make rest recommendations as they see fit. An internal survey of physician practice found that the vast majority of physicians instruct patients rest for 1-2 days, then to return to school and physical activity after the patient's symptoms have resolved. The amount of rest will vary from patients to patient based on variation in symptom resolution and patient compliance. This advice is consistent with best practices outlined by the CDC.

Group Type NO_INTERVENTION

No interventions assigned to this group

Intervention

Mandated Rest.

Group Type EXPERIMENTAL

Mandated Rest, Intervention

Intervention Type BEHAVIORAL

In addition to CDC based discharge instructions, the intervention group will receive instructions with strict activity restriction explicitly stating "No return to school" and "No Physical Activity" for the next five days. Patients and parents in the intervention group will be provided school and work excuses for the five days post-injury.

Interventions

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Mandated Rest, Intervention

In addition to CDC based discharge instructions, the intervention group will receive instructions with strict activity restriction explicitly stating "No return to school" and "No Physical Activity" for the next five days. Patients and parents in the intervention group will be provided school and work excuses for the five days post-injury.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* 11-22 years
* present to the Emergency Department within 24 hours of a head injury

Exclusion Criteria

* patients who are being admitted,
* non-English speaking patient/family,
* mental retardation (IQ \< 70)
* Suspected intoxication
* restricted used of dominant hand or limited vision
* injury or conditions affecting balance assessment
* prior mental defect or disease (e.g., developmental delay, learning disability, or moderate to severe cerebral palsy)
* known intracranial injury (e.g., intracranial bleeding, cerebral contusion)
* patients for whom a legal guardian is not present or cannot be contacted.
* ED clinician preference
Minimum Eligible Age

11 Years

Maximum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical College of Wisconsin

OTHER

Sponsor Role lead

Responsible Party

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Danny Thomas

Assistant Professor of Pediatrics

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Danny G Thomas, MD, MPH

Role: PRINCIPAL_INVESTIGATOR

Medical College of Wisconsin

Locations

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Children's Hospital of Wisconsin

Milwaukee, Wisconsin, United States

Site Status

Countries

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United States

References

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Sufrinko AM, Kontos AP, Apps JN, McCrea M, Hickey RW, Collins MW, Thomas DG. The Effectiveness of Prescribed Rest Depends on Initial Presentation After Concussion. J Pediatr. 2017 Jun;185:167-172. doi: 10.1016/j.jpeds.2017.02.072. Epub 2017 Mar 29.

Reference Type DERIVED
PMID: 28365025 (View on PubMed)

Silverberg ND, Iverson GL, McCrea M, Apps JN, Hammeke TA, Thomas DG. Activity-Related Symptom Exacerbations After Pediatric Concussion. JAMA Pediatr. 2016 Oct 1;170(10):946-953. doi: 10.1001/jamapediatrics.2016.1187.

Reference Type DERIVED
PMID: 27479847 (View on PubMed)

Thomas DG, Apps JN, Hoffmann RG, McCrea M, Hammeke T. Benefits of strict rest after acute concussion: a randomized controlled trial. Pediatrics. 2015 Feb;135(2):213-23. doi: 10.1542/peds.2014-0966. Epub 2015 Jan 5.

Reference Type DERIVED
PMID: 25560444 (View on PubMed)

Other Identifiers

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5520163IRC

Identifier Type: -

Identifier Source: org_study_id