Prefrontal Cortex and Abstract Thinking

NCT ID: NCT01100281

Last Updated: 2011-12-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

69 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-04-30

Study Completion Date

2011-04-30

Brief Summary

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The capacity of concept formation is not well understood, even if a link is supposed with the functioning of the frontal lobes.

Our aim is to better understand the cognitive mechanisms underlying this function and to try to correlate the performance with atrophy of the frontal lobe in neurodegenerative diseases involving this region (frontotemporal lobar degeneration and progressive supranuclear palsy).

Detailed Description

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Conditions

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Abstract Thinking Concept Formation

Keywords

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prefrontal cortex

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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PSP (Progressive supranuclear palsy)

Neuropsychological examination

Intervention Type BEHAVIORAL

Examination including especially concept formation

MRI

Intervention Type OTHER

MRI performed in T1-weighted three dimensional sequence

FTD (Frontotemporal lobar degenerative)

Neuropsychological examination

Intervention Type BEHAVIORAL

Examination including especially concept formation

MRI

Intervention Type OTHER

MRI performed in T1-weighted three dimensional sequence

Alzheimer's disease

Neuropsychological examination

Intervention Type BEHAVIORAL

Examination including especially concept formation

MRI

Intervention Type OTHER

MRI performed in T1-weighted three dimensional sequence

Interventions

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Neuropsychological examination

Examination including especially concept formation

Intervention Type BEHAVIORAL

MRI

MRI performed in T1-weighted three dimensional sequence

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* informed consent signed
* MMSE\> 20
* No contra indication to MRI

Exclusion Criteria

* MMSE\<20
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Institut National de la Santé Et de la Recherche Médicale, France

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Richard Levy, MD

Role: STUDY_DIRECTOR

Institut National de la Santé Et de la Recherche Médicale, France

Locations

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Inserm U 975

Paris, , France

Site Status

Countries

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France

Other Identifiers

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C09-29

Identifier Type: -

Identifier Source: org_study_id