Trial Outcomes & Findings for Cell Phone Intervention in Young Adults (NCT NCT01092364)

NCT ID: NCT01092364

Last Updated: 2017-11-13

Results Overview

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

365 participants

Primary outcome timeframe

Baseline and 24 months

Results posted on

2017-11-13

Participant Flow

Participant milestones

Participant milestones
Measure
Cell Phone Intervention
Behavioral lifestyle intervention for weight loss, delivered by cell phone. Behavioral weight loss intervention: Behavioral lifestyle intervention for weight loss, compared to advice-only control.
Personal Counseling Intervention
Behavioral lifestyle intervention for weight loss, delivered by personal counseling. Behavioral weight loss intervention: Behavioral lifestyle intervention for weight loss, compared to advice-only control.
Advice Only
Advice only control group.
Overall Study
STARTED
122
120
123
Overall Study
COMPLETED
104
104
105
Overall Study
NOT COMPLETED
18
16
18

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Waist circumference is presented by gender.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Cell Phone Intervention
n=122 Participants
Behavioral lifestyle intervention for weight loss, delivered by cell phone. Behavioral weight loss intervention: Behavioral lifestyle intervention for weight loss, compared to advice-only control.
Personal Counseling Intervention
n=120 Participants
Behavioral lifestyle intervention for weight loss, delivered by personal counseling. Behavioral weight loss intervention: Behavioral lifestyle intervention for weight loss, compared to advice-only control.
Advice Only
n=123 Participants
Advice only control group.
Total
n=365 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=122 Participants
0 Participants
n=120 Participants
0 Participants
n=123 Participants
0 Participants
n=365 Participants
Age, Categorical
Between 18 and 65 years
122 Participants
n=122 Participants
120 Participants
n=120 Participants
123 Participants
n=123 Participants
365 Participants
n=365 Participants
Age, Categorical
>=65 years
0 Participants
n=122 Participants
0 Participants
n=120 Participants
0 Participants
n=123 Participants
0 Participants
n=365 Participants
Age, Continuous
29.2 years
STANDARD_DEVIATION 4.2 • n=122 Participants
29.4 years
STANDARD_DEVIATION 4.3 • n=120 Participants
29.6 years
STANDARD_DEVIATION 4.3 • n=123 Participants
29.4 years
STANDARD_DEVIATION 4.3 • n=365 Participants
Sex: Female, Male
Female
84 Participants
n=122 Participants
85 Participants
n=120 Participants
85 Participants
n=123 Participants
254 Participants
n=365 Participants
Sex: Female, Male
Male
38 Participants
n=122 Participants
35 Participants
n=120 Participants
38 Participants
n=123 Participants
111 Participants
n=365 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
9 Participants
n=122 Participants
7 Participants
n=120 Participants
5 Participants
n=123 Participants
21 Participants
n=365 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
113 Participants
n=122 Participants
113 Participants
n=120 Participants
118 Participants
n=123 Participants
344 Participants
n=365 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=122 Participants
0 Participants
n=120 Participants
0 Participants
n=123 Participants
0 Participants
n=365 Participants
Race (NIH/OMB)
American Indian or Alaska Native
1 Participants
n=122 Participants
1 Participants
n=120 Participants
0 Participants
n=123 Participants
2 Participants
n=365 Participants
Race (NIH/OMB)
Asian
5 Participants
n=122 Participants
2 Participants
n=120 Participants
5 Participants
n=123 Participants
12 Participants
n=365 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=122 Participants
0 Participants
n=120 Participants
0 Participants
n=123 Participants
0 Participants
n=365 Participants
Race (NIH/OMB)
Black or African American
42 Participants
n=122 Participants
48 Participants
n=120 Participants
42 Participants
n=123 Participants
132 Participants
n=365 Participants
Race (NIH/OMB)
White
68 Participants
n=122 Participants
65 Participants
n=120 Participants
70 Participants
n=123 Participants
203 Participants
n=365 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=122 Participants
3 Participants
n=120 Participants
3 Participants
n=123 Participants
6 Participants
n=365 Participants
Race (NIH/OMB)
Unknown or Not Reported
6 Participants
n=122 Participants
1 Participants
n=120 Participants
3 Participants
n=123 Participants
10 Participants
n=365 Participants
Region of Enrollment
United States
122 Participants
n=122 Participants
120 Participants
n=120 Participants
123 Participants
n=123 Participants
365 Participants
n=365 Participants
Weight
102.4 kg
STANDARD_DEVIATION 25.2 • n=122 Participants
99.3 kg
STANDARD_DEVIATION 23.4 • n=120 Participants
101.3 kg
STANDARD_DEVIATION 22.6 • n=123 Participants
101.0 kg
STANDARD_DEVIATION 23.7 • n=365 Participants
BMI
35.7 Kg/m^2
STANDARD_DEVIATION 8.2 • n=122 Participants
34.9 Kg/m^2
STANDARD_DEVIATION 7.5 • n=120 Participants
35.1 Kg/m^2
STANDARD_DEVIATION 7.5 • n=123 Participants
35.2 Kg/m^2
STANDARD_DEVIATION 7.8 • n=365 Participants
Waist Circumference
Males
113.8 cm
STANDARD_DEVIATION 17.9 • n=38 Participants • Waist circumference is presented by gender.
111.5 cm
STANDARD_DEVIATION 16.4 • n=35 Participants • Waist circumference is presented by gender.
109.8 cm
STANDARD_DEVIATION 14.6 • n=38 Participants • Waist circumference is presented by gender.
111.7 cm
STANDARD_DEVIATION 16.3 • n=111 Participants • Waist circumference is presented by gender.
Waist Circumference
Females
109.3 cm
STANDARD_DEVIATION 18.4 • n=84 Participants • Waist circumference is presented by gender.
107.4 cm
STANDARD_DEVIATION 16.4 • n=85 Participants • Waist circumference is presented by gender.
107.9 cm
STANDARD_DEVIATION 15.7 • n=85 Participants • Waist circumference is presented by gender.
108.2 cm
STANDARD_DEVIATION 16.8 • n=254 Participants • Waist circumference is presented by gender.
Dietary intake
51.6 Scores on the HEI scale
STANDARD_DEVIATION 4.2 • n=122 Participants
50.8 Scores on the HEI scale
STANDARD_DEVIATION 3.6 • n=120 Participants
50.7 Scores on the HEI scale
STANDARD_DEVIATION 4.4 • n=123 Participants
51.0 Scores on the HEI scale
STANDARD_DEVIATION 4.1 • n=365 Participants
Physical activity
756.0 kcal/week
STANDARD_DEVIATION 846.1 • n=122 Participants
1009.3 kcal/week
STANDARD_DEVIATION 1346.4 • n=120 Participants
865.9 kcal/week
STANDARD_DEVIATION 1133.9 • n=123 Participants
879.7 kcal/week
STANDARD_DEVIATION 1134.2 • n=365 Participants

PRIMARY outcome

Timeframe: Baseline and 24 months

Population: Intention to treat

Outcome measures

Outcome measures
Measure
Cell Phone Intervention
n=122 Participants
Behavioral lifestyle intervention for weight loss, delivered by cell phone. Behavioral weight loss intervention: Behavioral lifestyle intervention for weight loss, compared to advice-only control.
Personal Counseling Intervention
n=120 Participants
Behavioral lifestyle intervention for weight loss, delivered by personal counseling. Behavioral weight loss intervention: Behavioral lifestyle intervention for weight loss, compared to advice-only control.
Advice Only
n=123 Participants
Advice only control group.
Change in Body Weight
-0.99 kg
Standard Deviation 6.2
-2.6 kg
Standard Deviation 6.0
-1.7 kg
Standard Deviation 8.3

Adverse Events

Cell Phone Intervention

Serious events: 4 serious events
Other events: 8 other events
Deaths: 0 deaths

Personal Counseling Intervention

Serious events: 4 serious events
Other events: 4 other events
Deaths: 0 deaths

Advice Only

Serious events: 5 serious events
Other events: 1 other events
Deaths: 0 deaths

Serious adverse events

Serious adverse events
Measure
Cell Phone Intervention
n=122 participants at risk
Behavioral lifestyle intervention for weight loss, delivered by cell phone. Behavioral weight loss intervention: Behavioral lifestyle intervention for weight loss, compared to advice-only control.
Personal Counseling Intervention
n=120 participants at risk
Behavioral lifestyle intervention for weight loss, delivered by personal counseling. Behavioral weight loss intervention: Behavioral lifestyle intervention for weight loss, compared to advice-only control.
Advice Only
n=123 participants at risk
Advice only control group.
Gastrointestinal disorders
Cholecystectomy
0.00%
0/122 • 24 months
0.83%
1/120 • Number of events 1 • 24 months
0.00%
0/123 • 24 months
Psychiatric disorders
Psychiatric hospitalization
0.00%
0/122 • 24 months
0.00%
0/120 • 24 months
0.81%
1/123 • Number of events 1 • 24 months
Pregnancy, puerperium and perinatal conditions
Obstetric hospitalization
0.00%
0/122 • 24 months
0.00%
0/120 • 24 months
1.6%
2/123 • Number of events 2 • 24 months
General disorders
Other
3.3%
4/122 • Number of events 4 • 24 months
2.5%
3/120 • Number of events 3 • 24 months
1.6%
2/123 • Number of events 2 • 24 months

Other adverse events

Other adverse events
Measure
Cell Phone Intervention
n=122 participants at risk
Behavioral lifestyle intervention for weight loss, delivered by cell phone. Behavioral weight loss intervention: Behavioral lifestyle intervention for weight loss, compared to advice-only control.
Personal Counseling Intervention
n=120 participants at risk
Behavioral lifestyle intervention for weight loss, delivered by personal counseling. Behavioral weight loss intervention: Behavioral lifestyle intervention for weight loss, compared to advice-only control.
Advice Only
n=123 participants at risk
Advice only control group.
Musculoskeletal and connective tissue disorders
Musculoskeletal injury
6.6%
8/122 • Number of events 8 • 24 months
3.3%
4/120 • Number of events 4 • 24 months
0.81%
1/123 • Number of events 1 • 24 months

Additional Information

Dr. Laura P. Svetkey

Duke University Medical Center

Phone: 919-660-6626

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place