Comparison of Lidocaine and Remifentanil for the Effect on Responses to the Endotracheal Tube During Emergence From General Anesthesia

NCT ID: NCT01082458

Last Updated: 2010-11-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

67 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-02-28

Study Completion Date

2010-07-31

Brief Summary

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Target concentration infusion(TCI) of remifentanil (2.0ng/ml) suppresses the cough induced by endotracheal tube more effectively than intravenous administration of lidocaine (1.5mg/kg).

Detailed Description

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Conditions

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Thyroidectomy

Keywords

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Patients scheduled to undergo thyroidectomy

Study Design

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Primary Study Purpose

PREVENTION

Interventions

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remifentanil / lidocaine

Remifentanil TCI group : target controlled infusion of 2.0ng/ml of remifentanil on end of surgery.

Lidocaine IV group : Intravenous administration of 1.5mg/kg of lidocaine on end of surgery.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Females older than 20 years old

Exclusion Criteria

* Patients with acute or chronic respiratory disease, hypertension, gastro-esophageal reflux disease, having preoperative sedatives or mucolytics, and current smoker.
Minimum Eligible Age

20 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Yonsei University

OTHER

Sponsor Role lead

Responsible Party

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Anesthesiology and Pain Medicine

Locations

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Severance Hospital

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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4-2009-0519

Identifier Type: -

Identifier Source: org_study_id