Trial Outcomes & Findings for Efficacy of Statins In Prevention of CIN (NCT NCT01071993)

NCT ID: NCT01071993

Last Updated: 2017-12-04

Results Overview

Development of CIN (Contrast-induced Nephropathy) Defined as a Postprocedure Increase in Serum Creatinine of \> 0.5 mg/dL or \>25% Increase From Baseline at 24 \& at 48 Hours

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

21 participants

Primary outcome timeframe

48 hours

Results posted on

2017-12-04

Participant Flow

Participants were recruited and signed consent. No drugs were supplied to participants. Study sponsor could not provide study drugs to participants due to cost restraints.

Prior to assigning participants to specific arms of the protocol, site was informed that the study drug was no longer available.

Participant milestones

Participant milestones
Measure
Atorvastatin
atorvastatin: pre-treatment with atorvastatin (80 mg 12 hours prior to the procedure and 40 mg pre-procedure)
Placebo
placebo: pre-treatment with placebo (80 mg 12 hours prior to the procedure and 40 mg pre-procedure)
Overall Study
STARTED
0
0
Overall Study
COMPLETED
0
0
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Efficacy of Statins In Prevention of CIN

Baseline characteristics by cohort

Baseline data not reported

PRIMARY outcome

Timeframe: 48 hours

Population: Participants signed consent; however, study was terminated prior to randomization

Development of CIN (Contrast-induced Nephropathy) Defined as a Postprocedure Increase in Serum Creatinine of \> 0.5 mg/dL or \>25% Increase From Baseline at 24 \& at 48 Hours

Outcome measures

Outcome data not reported

Adverse Events

Atorvastatin

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Placebo

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Mazen Abu-Fadel, MD

University of Oklahoma

Phone: 405-271-4742

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place