Trial Outcomes & Findings for Trendelenburg's Slide Prevention Study (NCT NCT01068821)

NCT ID: NCT01068821

Last Updated: 2012-05-15

Results Overview

Patients undergoing gynecologic surgery require steep (30 to 45 degree) Trendelenberg's position to allow adequate exposure of the pelvis. This position leads to a small amount of movement toward the head of the bed. The table was marked at the point of the anterior superior iliac spine (ASIS) and at the point where a vertical marker touching the acromioclavicular (AC) joint of the left shoulder drops to the table. At the end of the surgery, when the operating table is leveled, the final positions of ASIS and AC will be measured. Measurements were made in centimeters to the tenth position.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

60 participants

Primary outcome timeframe

About 150 minutes after start of surgery

Results posted on

2012-05-15

Participant Flow

Patients with planned laparoscopic or robotic procedures were offered participation in the preoperative holding area. Recruitment started 3/1/2010 and ended 5/10/2010.

Patients were enrolled if they acknowledged their desire to participate. Patients were excluded if they were brought to the operating room before being approached for participation or if they indicated they did not wish to participate. The materials being compared are already both commonly used for gynecologic surgery.

Participant milestones

Participant milestones
Measure
Egg Crate Foam Mattress
Patients will be placed on egg-crate foam mattress instead of a gel pad by randomization. All other positioning and measurements, including outcomes measures will be the same as for the the primary experimental intervention (gel pad).
Gel Pad
Patients will be placed on gel mattress instead of egg-crate foam mattress by randomization. All other positioning and measurements, including outcomes measures will be the same as for the the primary experimental intervention (gel pad).
Overall Study
STARTED
31
29
Overall Study
COMPLETED
30
29
Overall Study
NOT COMPLETED
1
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Trendelenburg's Slide Prevention Study

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Egg Crate Foam Mattress
n=31 Participants
Patients will be placed on egg-crate foam mattress instead of a gel pad by randomization. All other positioning and measurements, including outcomes measures will be the same as for the the primary experimental intervention (gel pad).
Gel Pad
n=29 Participants
Patients will be placed on gel mattress instead of egg-crate foam mattress by randomization. All other positioning and measurements, including outcomes measures will be the same as for the the primary experimental intervention (gel pad).
Total
n=60 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
23 Participants
n=5 Participants
22 Participants
n=7 Participants
45 Participants
n=5 Participants
Age, Categorical
>=65 years
8 Participants
n=5 Participants
7 Participants
n=7 Participants
15 Participants
n=5 Participants
Age Continuous
55.5 years
STANDARD_DEVIATION 11.8 • n=5 Participants
53.6 years
STANDARD_DEVIATION 12.7 • n=7 Participants
54.6 years
STANDARD_DEVIATION 12.2 • n=5 Participants
Sex: Female, Male
Female
31 Participants
n=5 Participants
29 Participants
n=7 Participants
60 Participants
n=5 Participants
Sex: Female, Male
Male
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Region of Enrollment
United States
31 participants
n=5 Participants
29 participants
n=7 Participants
60 participants
n=5 Participants

PRIMARY outcome

Timeframe: About 150 minutes after start of surgery

Population: Study size calculation was performed for 80% power, and p=0.05

Patients undergoing gynecologic surgery require steep (30 to 45 degree) Trendelenberg's position to allow adequate exposure of the pelvis. This position leads to a small amount of movement toward the head of the bed. The table was marked at the point of the anterior superior iliac spine (ASIS) and at the point where a vertical marker touching the acromioclavicular (AC) joint of the left shoulder drops to the table. At the end of the surgery, when the operating table is leveled, the final positions of ASIS and AC will be measured. Measurements were made in centimeters to the tenth position.

Outcome measures

Outcome measures
Measure
Egg Crate Foam Mattress
n=30 Participants
Patient positioned on egg crate foam mattress during surgery
Gel Pad
n=29 Participants
Patient positioned on gel pad during surgery
Amount of Patient Movement on the Operating Room Table
3.2 centimeters
Standard Deviation 1.9
4.5 centimeters
Standard Deviation 4.0

SECONDARY outcome

Timeframe: postoperative day 1 and postoperative week 3-8

Population: Participants were analyzed per protocol if they returned for postoperative followup (59 of 60 were analyzed)

The neurologic deficit was assessed as follows: Patients' postoperative care was unchanged from routine for this study. Any postoperative complaints regarding limb pain or weakness or numbness were recorded and assessed with neurologic exam to determine sensation or motor components. Absence of resolution was documented.

Outcome measures

Outcome measures
Measure
Egg Crate Foam Mattress
n=30 Participants
Patient positioned on egg crate foam mattress during surgery
Gel Pad
n=29 Participants
Patient positioned on gel pad during surgery
Number of Participants Reporting a Neurologic Deficit in Extremities After Surgery
0 participants
0
3 participants
0.19

Adverse Events

Egg Crate Foam Mattress

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Gel Pad

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Mary Ellen Wechter

Mayo Clinic, Florida

Phone: 904 412 7351

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place