Teriparatide for Improved Knee Prosthesis Fixation

NCT ID: NCT01063504

Last Updated: 2013-06-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-02-28

Study Completion Date

2013-06-30

Brief Summary

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The investigators will study how well knee joint prostheses become fixed to the bone when patients get teriparatide, compared to placebo. Measurements will use high resolution 3D radiography (radiostereometry, RSA).

Detailed Description

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Conditions

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Osteoarthritis of the Knee

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Teriparatide 20 microgram daily for 2 months

Group Type ACTIVE_COMPARATOR

teriparatide

Intervention Type DRUG

Placebo

Group Type PLACEBO_COMPARATOR

teriparatide

Intervention Type DRUG

Interventions

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teriparatide

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Osteoarthritis of the knee planned for prosthesis surgery

Exclusion Criteria

* Poor health, drugs affecting bone metabolism.
Minimum Eligible Age

60 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Linkoeping

OTHER

Sponsor Role lead

Responsible Party

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Per Aspenberg

professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Motala hospital

Motala, , Sweden

Site Status

Countries

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Sweden

Other Identifiers

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PTHKnee

Identifier Type: -

Identifier Source: org_study_id

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