ELAZOP Switching Study in Korea

NCT ID: NCT01055366

Last Updated: 2012-12-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

96 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-03-31

Study Completion Date

2011-12-31

Brief Summary

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The purpose of this study is to assess the safety and efficacy of switching to ELAZOP from prior pharmacotherapy in patients with open-angled glaucoma.

Detailed Description

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Conditions

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Open Angle Glaucoma

Keywords

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Open angle glaucoma OAG Elazop Azarga Brinzolamide/Timolol combination

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Elazop (Azarga)

Elazop Treatment arm

Group Type EXPERIMENTAL

Elazop (Azarga)

Intervention Type DRUG

Administer one drop of ELAZOP in treated eye(s) twice a day for up to 12 weeks

Interventions

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Elazop (Azarga)

Administer one drop of ELAZOP in treated eye(s) twice a day for up to 12 weeks

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* 18 years of age or older.
* Clinical diagnosis of ocular hypertension, primary open-angle or pigment dispersion glaucoma in both eyes.
* Must be on a stable regimen of Intraocular Pressure (IOP) lowering medication (i.e., either a single therapeutic agent or two separate ocular hypotensive agents) for at least one month prior to the Screening Visit.
* Must have IOP considered to be safe (in the opinion of the investigator), in both eyes, in such a way that should assure clinical stability of vision and the optic nerve throughout the study period.
* Must be willing to discontinue the use of all other ocular hypotensive medications prior to receiving the study medication for the entire course of the study.

Exclusion Criteria

* Known medical history of allergy, hypersensitivity, or poor tolerance to any component of the preparations to be used in the study that is deemed clinically significant in the opinion of the Principal Investigator.
* Intraocular conventional surgery or laser surgery in either eye less than three months prior to the Screening visit.
* History of ocular herpes simplex.
* Pregnant or lactating.
* Participation in any other investigational study within 30 days of Screening visit.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alcon Research

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Youngnam Univ. Hospital

Daegu, Daegu, South Korea

Site Status

Seoul National University Bundang Hospital

Sungnam, Gyounggi, South Korea

Site Status

Seoul National University Hospital

Seoul, , South Korea

Site Status

Yonsei University Severance Hospital

Seoul, , South Korea

Site Status

Samsung Medical Center

Seoul, , South Korea

Site Status

Yonsei University Kangnam Severance Hospital

Seoul, , South Korea

Site Status

Seoul St. Mary's Hospital, The Catholic University of Korea

Seoul, , South Korea

Site Status

Asan Medical Center

Seoul, , South Korea

Site Status

Kim's Eye Hospital

Seoul, , South Korea

Site Status

St. Mary's Hospital, The Catholic University of Korea

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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RM-09-06

Identifier Type: -

Identifier Source: org_study_id