Study to Assess the Effectiveness and Safety of FLECTOR Patch for Treatment of Acute Back Strain

NCT ID: NCT01054820

Last Updated: 2012-08-16

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

123 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-01-31

Study Completion Date

2010-03-31

Brief Summary

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Although approved for minor strains, sprains and contusions, FLECTOR Patch has not been studied extensively in the setting of acute back strain. This study is being conducted as an initial step in demonstrating the benefit of FLECTOR Patch specifically for back strain. In particular, this study is expected to provide information about the amount of improvement in back strain among subjects using the FLECTOR Patch, which may then be used to inform subsequent studies.

Detailed Description

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Conditions

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Acute Back Strain

Keywords

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FLECTOR® Patch acute back strain

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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FLECTORA Patch (diclofenac epolamine topical patch) 1.3%

One patch applied every 12 hours

Group Type EXPERIMENTAL

FLECTOR® Patch (diclofenac epolamine topical patch) 1.3%

Intervention Type DRUG

One FLECTOR Patch applied to the most painful area on the subject's back every 12 hours for up to 14 days.

Interventions

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FLECTOR® Patch (diclofenac epolamine topical patch) 1.3%

One FLECTOR Patch applied to the most painful area on the subject's back every 12 hours for up to 14 days.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

Participants in the study must:

1. have acute, non-radicular back strain with onset up to 10 days before the first visit
2. have intact, non-damaged skin at the proposed patch application site
3. be untreated or unresponsive to conservative pain treatment regimens and/or opioids
4. have a minimum pain intensity score of four (4) or more on a scale of 1-10 (a rating of zero (0) being "no pain" and a rating of ten (10) being "pain as bad as you can imagine")
5. have a normal neurologic examination

Exclusion Criteria

Participants may not be in the study if they:

1. have had surgery or other chronic pain condition within 3 months before first treatment
2. have back pain radiating below the knee at time of enrollment
3. have neuropathic pain or have been treated with gabapentin or pregabalin for neuropathy
4. are being treated for or are known to currently have kidney or liver disease
5. have certain other diseases or are using certain types of other drugs.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Pfizer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pfizer CT.gov Call Center

Role: STUDY_DIRECTOR

Pfizer

Countries

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United States

Related Links

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Other Identifiers

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B4811001

Identifier Type: -

Identifier Source: secondary_id

K353-09-4001

Identifier Type: -

Identifier Source: org_study_id