Vitamin D Levels and Postoperative Hypocalcemia After Total Thyroidectomy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-12-31

Study Completion Date

2010-05-31

Brief Summary

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Hypocalcemia is one of the most frequent complications of total thyroidectomy, a procedure used for benign as well as malignant conditions of the thyroid gland. Postoperative hypocalcemia is usually caused by hypoparathyroidism. Vitamin D is implicated in calcium metabolism as it increases intestinal calcium transport and regulates parathormone production. Aim of the present study is to evaluate preoperative vitamin D levels as a prognostic factor for postoperative hypocalcemia and hypoparathyroidism.

Detailed Description

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Conditions

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Hypocalcemia Hypoparathyroidism Vitamin D Deficiency Thyroidectomy

Keywords

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Hypocalcemia Hypoparathyroidism Vitamin D deficiency Total thyroidectomy calcium PTH

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Total Thyroidectomy

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Patient is over 18 years old
2. Patient scheduled for total thyroidectomy
3. Patient signs and dates a written informed consent form (ICF) and indicates an understanding of the study procedures

Exclusion Criteria

1. Primary hyperparathyroidism
2. Primary hypoparathyroidism
3. Chronic Renal Failure
4. Hypoalbuminemia
5. Neck irradiation
6. Systematic Diseases (e.g., infections)
7. Thyroid or parathyroid cancer
8. Osteoporosis
9. Drugs that influence calcium metabolism (vitamin D analogues, oral calcium supplements, biphosphonates, teriparatide, thiazide diuretics)

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Third Surgical Clinic, AHEPA University Hospital

Principal Investigators

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Spyros T Papavramidis, Prof

Role: STUDY_DIRECTOR

Aristotle University Of Thessaloniki

Locations

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AHEPA University Hospital Thessaloniki, Greece

Thessaloniki, Makedonia, Greece

Site Status RECRUITING

Countries

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Greece

Central Contacts

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Theodossis S Papavramidis, MD, PhD

Role: CONTACT

Phone: 00302310993197

Email: [email protected]

Olympia E Anastasiou, MD