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Attempts to Stop/Reduce Marijuana Among Dependent Users

NCT ID: NCT01039415

Last Updated: 2016-10-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

234 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-06-30

Study Completion Date

2012-10-31

Brief Summary

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The purpose of the study is to determine why and how marijuana users stop or reduce their marijuana use.

Detailed Description

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The major aim of this study is to provide a better understanding of attempts to stop or reduce marijuana use that can be used to develop better behavioral treatments for marijuana dependence. The application will focus on adult daily marijuana users who try to stop or reduce their marijuana use in a real-world setting. Although prospective, natural history studies describing attempts to stop or reduce alcohol, heroin and tobacco use have proved useful, we know of no such study among adult marijuana users. Two pilot studies will develop measures and assess compliance with our procedures. The main study will recruit up to 400 adult marijuana smokers with the goal of a sample size of 200 participants with adequate compliance. Participants will call an Interactive Voice Recording (IVR) system daily for 3 months to report marijuana use, quit/reduction attempts, and events that might increase or decrease the probability of initiating a quit/reduction attempt or the success of an attempt. Follow-up at 6 months will track recent marijuana and other drug use. Knowing what motivates marijuana users to try to stop or reduce, and knowing which strategies for stopping marijuana use are successful, can help develop treatments for marijuana dependence. For example, if stopping tobacco when trying to stop marijuana decreases the chance of stopping marijuana, then smoking cessation should be done after stopping marijuana. Or if reducing marijuana often leads to cessation, then convincing those not interested in quitting marijuana to first try reducing may be helpful.

Conditions

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Marijuana Abuse Marijuana Dependence

Keywords

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marijuana marijuana abuse marijuana dependence cannabis substance-related disorder abstinence

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* daily marijuana smokers for at least 1 year

Exclusion Criteria

* pregnant women
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Institute on Drug Abuse (NIDA)

NIH

Sponsor Role collaborator

University of Vermont

OTHER

Sponsor Role lead

Responsible Party

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John Hughes

Professor of psychiatry

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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John Hughes, MD

Role: PRINCIPAL_INVESTIGATOR

University of Vermont

Locations

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University of Vermont

Burlington, Vermont, United States

Site Status

Countries

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United States

References

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Hughes JR, Fingar JR, Budney AJ, Naud S, Helzer JE, Callas PW. Marijuana use and intoxication among daily users: an intensive longitudinal study. Addict Behav. 2014 Oct;39(10):1464-70. doi: 10.1016/j.addbeh.2014.05.024. Epub 2014 Jun 4.

Reference Type RESULT
PMID: 24935797 (View on PubMed)

Hughes JR, Naud S, Budney AJ, Fingar JR, Callas PW. Attempts to stop or reduce daily cannabis use: An intensive natural history study. Psychol Addict Behav. 2016 May;30(3):389-97. doi: 10.1037/adb0000155. Epub 2016 Feb 1.

Reference Type RESULT
PMID: 26828641 (View on PubMed)

Hughes JR, Naud S, Budney AJ, Fingar JR, Callas PW. Environmental cues and attempts to change in daily cannabis users: An intensive longitudinal study. Drug Alcohol Depend. 2016 Apr 1;161:15-20. doi: 10.1016/j.drugalcdep.2015.09.033. Epub 2016 Feb 6.

Reference Type RESULT
PMID: 26872879 (View on PubMed)

Other Identifiers

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R01DA024691

Identifier Type: NIH

Identifier Source: secondary_id

View Link

CHRBS #09-005

Identifier Type: -

Identifier Source: org_study_id