Intervention With Legume Kernel Fibre in Healthy Subjects
NCT ID: NCT01036308
Last Updated: 2012-11-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
76 participants
INTERVENTIONAL
2007-07-31
2007-12-31
Brief Summary
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Detailed Description
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Seventy-eight healthy volunteers were enrolled. Seventy-six subjects (mean age of 24 years, 55 women and 21 men) completed the double-blind, randomized crossover trial. After two weeks run-in period, half of the volunteers consumed 25 g of legume fibres (Boregine, TypTop or Soy fibre) every day, and the other half received a reference fibre product (citrus fibre, Herbacel AQ Plus) for a period of two weeks. After two weeks wash-out the intervention changed between the groups.
At the end of each period a quantitative stool and urine collection took place and fasting blood samples were drawn.
Conditions
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Keywords
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Study Design
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RANDOMIZED
CROSSOVER
PREVENTION
QUADRUPLE
Study Groups
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TypTop
Lupinus albus Typ Top (lupin kernel fibre, dietary fibre content: 83%)
pure fibre-product
The subjects consumed 25 g pure fibre-product per day over two weeks. One half a portion of the fibres was stirred into a selected milk product and the other half in juice.
reference fibre
The subjects consumed 25 g reference fibre (citrus fibre: Herbacel AQ Plus; Herbafood Ingredients) per day over two weeks. One half a portion of the fibres was stirred into a selected milk product and the other half in juice.
Soy fibre
Glycine max Hefeng (soy fibre; dietary fibre content: 77%)
pure fibre-product
The subjects consumed 25 g pure fibre-product per day over two weeks. One half a portion of the fibres was stirred into a selected milk product and the other half in juice.
reference fibre
The subjects consumed 25 g reference fibre (citrus fibre: Herbacel AQ Plus; Herbafood Ingredients) per day over two weeks. One half a portion of the fibres was stirred into a selected milk product and the other half in juice.
Boregine
Lupinus angustifolius Boregine (lupin kernel fibre, dietary fibre content: 87%)
pure fibre-product
The subjects consumed 25 g pure fibre-product per day over two weeks. One half a portion of the fibres was stirred into a selected milk product and the other half in juice.
reference fibre
The subjects consumed 25 g reference fibre (citrus fibre: Herbacel AQ Plus; Herbafood Ingredients) per day over two weeks. One half a portion of the fibres was stirred into a selected milk product and the other half in juice.
Interventions
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pure fibre-product
The subjects consumed 25 g pure fibre-product per day over two weeks. One half a portion of the fibres was stirred into a selected milk product and the other half in juice.
reference fibre
The subjects consumed 25 g reference fibre (citrus fibre: Herbacel AQ Plus; Herbafood Ingredients) per day over two weeks. One half a portion of the fibres was stirred into a selected milk product and the other half in juice.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* healthy subjects
Exclusion Criteria
* allergy against legumes
* intolerance against milk protein
* pregnancy, lactation
* chronic diseases
20 Years
45 Years
ALL
Yes
Sponsors
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German Federal Ministry of Education and Research
OTHER_GOV
University of Jena
OTHER
Responsible Party
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Friedrich Schiller University Jena, Department of Nutritional Physiology
Principal Investigators
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Gerhard Jahreis, Prof. Dr.
Role: PRINCIPAL_INVESTIGATOR
Friedrich Schiller University Jena, Institute of Nutrition, Department of Nutrional Physiology
Locations
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Friedrich Schiller University Jena, Institute of Nutrition, Department of Nutrional Physiology
Jena, Thuringia, Germany
Countries
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References
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Fechner A, Fenske K, Jahreis G. Effects of legume kernel fibres and citrus fibre on putative risk factors for colorectal cancer: a randomised, double-blind, crossover human intervention trial. Nutr J. 2013 Jul 16;12:101. doi: 10.1186/1475-2891-12-101.
Other Identifiers
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LSEP H32-07
Identifier Type: -
Identifier Source: org_study_id