Trial Outcomes & Findings for Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female Athletes (NCT NCT01034527)

NCT ID: NCT01034527

Last Updated: 2020-09-04

Results Overview

determine biomechanical risk factors for ACL injury and determine if participation in NMT reduces risk factors compared to sham (speed training)

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

593 participants

Primary outcome timeframe

2 years

Results posted on

2020-09-04

Participant Flow

School team recruitment

Participant milestones

Participant milestones
Measure
Neuromuscular Training
Combination of exercises and phases designed to initiate lateral trunk perturbations that force the athlete to decelerate and control the trunk in order to successfully perform the techniques. Neuromuscular Training: Combination of exercises and phases to initiate lateral trunk perturbations that force the athlete to decelerate and control the trunk in order to successfully perform the techniques.
Speed Training
Speed training protocol Sham training will consist of sagittal plane only running drills designs solely to enhance sprint speed. A sham sagittal plane sprint training protocol that will be instituted with the teams that are randomly selected for sham treatment. Five phases will be utilized to facilitate progressions designed to improve the athletes' forward sprinting speed. Training volume will be approximately equivalent for the TNMT and sham protocols. They each will take athletes approximately 30 minutes to complete
Overall Study
STARTED
307
216
Overall Study
COMPLETED
307
216
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female Athletes

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Neuromuscular Training
n=307 Participants
Combination of exercises and phases designed to initiate lateral trunk perturbations that force the athlete to decelerate and control the trunk in order to successfully perform the techniques. Neuromuscular Training: Combination of exercises and phases to initiate lateral trunk perturbations that force the athlete to decelerate and control the trunk in order to successfully perform the techniques.
Speed Training
n=216 Participants
Speed training protocol Sham training will consist of sagittal plane only running drills designs solely to enhance sprint speed. A sham sagittal plane sprint training protocol that will be instituted with the teams that are randomly selected for sham treatment. Five phases will be utilized to facilitate progressions designed to improve the athletes' forward sprinting speed. Training volume will be approximately equivalent for the TNMT and sham protocols. They each will take athletes approximately 30 minutes to complete
Total
n=523 Participants
Total of all reporting groups
Age, Categorical
<=18 years
307 Participants
n=5 Participants
216 Participants
n=7 Participants
523 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Continuous
14.04 years
n=5 Participants
14.04 years
n=7 Participants
14.04 years
n=5 Participants
Sex: Female, Male
Female
307 Participants
n=5 Participants
216 Participants
n=7 Participants
523 Participants
n=5 Participants
Sex: Female, Male
Male
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Region of Enrollment
United States
307 participants
n=5 Participants
216 participants
n=7 Participants
523 participants
n=5 Participants

PRIMARY outcome

Timeframe: 2 years

determine biomechanical risk factors for ACL injury and determine if participation in NMT reduces risk factors compared to sham (speed training)

Outcome measures

Outcome measures
Measure
Neuromuscular Training
n=307 Participants
Combination of exercises and phases designed to initiate lateral trunk perturbations that force the athlete to decelerate and control the trunk in order to successfully perform the techniques. Neuromuscular Training: Combination of exercises and phases to initiate lateral trunk perturbations that force the athlete to decelerate and control the trunk in order to successfully perform the techniques.
Speed Training
n=216 Participants
Speed training protocol Sham training will consist of sagittal plane only running drills designs solely to enhance sprint speed. A sham sagittal plane sprint training protocol that will be instituted with the teams that are randomly selected for sham treatment. Five phases will be utilized to facilitate progressions designed to improve the athletes' forward sprinting speed. Training volume will be approximately equivalent for the TNMT and sham protocols. They each will take athletes approximately 30 minutes to complete
Number of Participants With Decrease in Knee Valgus Measurement
307 Participants
216 Participants

Adverse Events

Neuromuscular Training

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Speed Training

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Timothy Hewett

Mayo Clinic

Phone: 513-636-5971

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place