Omega-3 Fatty Acids and Health Effects

NCT ID: NCT01034423

Last Updated: 2015-02-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

69 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-09-30

Study Completion Date

2009-12-31

Brief Summary

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The investigators want to study health effects from omega-3 fatty acids, from fishoil with different quality.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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omega-3 high quality

Group Type EXPERIMENTAL

Omega-3

Intervention Type DIETARY_SUPPLEMENT

Capsules with omega-3 fatty acids.

sun flower oil

Intervention Type DIETARY_SUPPLEMENT

Capsules with sun flower oil.

omega-3 low quality

Group Type EXPERIMENTAL

Omega-3

Intervention Type DIETARY_SUPPLEMENT

Capsules with omega-3 fatty acids.

sun flower oil

Intervention Type DIETARY_SUPPLEMENT

Capsules with sun flower oil.

placebo

Group Type PLACEBO_COMPARATOR

Omega-3

Intervention Type DIETARY_SUPPLEMENT

Capsules with omega-3 fatty acids.

sun flower oil

Intervention Type DIETARY_SUPPLEMENT

Capsules with sun flower oil.

Interventions

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Omega-3

Capsules with omega-3 fatty acids.

Intervention Type DIETARY_SUPPLEMENT

sun flower oil

Capsules with sun flower oil.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Healthy individuals.

Exclusion Criteria

* Pregnant women, lactating women, chronic diseases and smoking.
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Oslo Metropolitan University

OTHER

Sponsor Role lead

Responsible Party

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Stine Marie Ulven

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Stine M Ulven, PhD

Role: STUDY_CHAIR

Oslo Metropolitan University

References

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Myhrstad MC, Ottestad I, Gunther CC, Ryeng E, Holden M, Nilsson A, Bronner KW, Kohler A, Borge GI, Holven KB, Ulven SM. The PBMC transcriptome profile after intake of oxidized versus high-quality fish oil: an explorative study in healthy subjects. Genes Nutr. 2016 May 31;11:16. doi: 10.1186/s12263-016-0530-6. eCollection 2016.

Reference Type DERIVED
PMID: 27551317 (View on PubMed)

Myhrstad MC, Ulven SM, Gunther CC, Ottestad I, Holden M, Ryeng E, Borge GI, Kohler A, Bronner KW, Thoresen M, Holven KB. Fish oil supplementation induces expression of genes related to cell cycle, endoplasmic reticulum stress and apoptosis in peripheral blood mononuclear cells: a transcriptomic approach. J Intern Med. 2014 Nov;276(5):498-511. doi: 10.1111/joim.12217. Epub 2014 Mar 20.

Reference Type DERIVED
PMID: 24641624 (View on PubMed)

Ottestad I, Hassani S, Borge GI, Kohler A, Vogt G, Hyotylainen T, Oresic M, Bronner KW, Holven KB, Ulven SM, Myhrstad MC. Fish oil supplementation alters the plasma lipidomic profile and increases long-chain PUFAs of phospholipids and triglycerides in healthy subjects. PLoS One. 2012;7(8):e42550. doi: 10.1371/journal.pone.0042550. Epub 2012 Aug 28.

Reference Type DERIVED
PMID: 22952598 (View on PubMed)

Ottestad I, Vogt G, Retterstol K, Myhrstad MC, Haugen JE, Nilsson A, Ravn-Haren G, Nordvi B, Bronner KW, Andersen LF, Holven KB, Ulven SM. Oxidised fish oil does not influence established markers of oxidative stress in healthy human subjects: a randomised controlled trial. Br J Nutr. 2012 Jul;108(2):315-26. doi: 10.1017/S0007114511005484. Epub 2011 Dec 5.

Reference Type DERIVED
PMID: 22136711 (View on PubMed)

Other Identifiers

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6.2008.2215

Identifier Type: -

Identifier Source: org_study_id

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