Safety and Efficacy of Oral Colostrum Derived Anti Influenza Antibodies in Healthy Volunteers

NCT ID: NCT01026350

Last Updated: 2009-12-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE1

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-01-31

Brief Summary

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Administration of colostrum enriched with anti-Flu antibodies may alter host's response to the flu virus.

Detailed Description

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Conditions

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Influenza

Keywords

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modulating immune response to flu antigen

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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study group

Group Type EXPERIMENTAL

colostrum enriched with anti flu antibodies

Intervention Type DIETARY_SUPPLEMENT

each volunteer will receive six 1.2 g oral tablets (equivalent to 600 mg of bovine colostrum powder each) once a day for two weeks.

Interventions

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colostrum enriched with anti flu antibodies

each volunteer will receive six 1.2 g oral tablets (equivalent to 600 mg of bovine colostrum powder each) once a day for two weeks.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Healthy male volunteers ages 18-60
* If participating in sexual activity that could lead to pregnancy, the study volunteer must agree that two reliable methods of contraception will be used simultaneously while receiving the protocol-specified medication and for 1 month after stopping the medication
* Men \> 18 years.
* Ability and willingness of subject to provide informed consent
* Screening tests' results within 15% of normal values

Exclusion Criteria

* Female
* Continuous use of the following medications for more than 3 days within 30 days of study entry:
* Immunosuppressives
* Immune modulators
* Systemic glucocorticoids
* Anti-neoplastic agents
* Active drug or alcohol use or dependence that, in the opinion of the site investigator, would interfere with adherence to study requirements.
* Serious illness requiring systemic treatment and/or hospitalization within 30 days prior to entry.
* Subjects with a clinically significant infectious, immune mediated or malignant disease
* Subjects with anemia (Hb \<10.5 gm/dl)
* Subjects with thrombocytopenia (platelets \<100K/µl)
* Subjects with lymphopenia (absolute lymphocyte count \<0.7)
* Subjects who were previously vaccinated against flu.
* Subject who received any vaccination within the last 6 months
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Hadassah Medical Organization

OTHER

Sponsor Role lead

Responsible Party

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Immuron Limited

Locations

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Hadassah Hebrew University Medical Center

Jerusalem, , Israel

Site Status

Countries

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Israel

Central Contacts

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tomer adar, MD

Role: CONTACT

Phone: 972-2-6778511

Email: [email protected]

Facility Contacts

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tomer adar, md

Role: primary

References

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Kim JH, Jung WS, Choi NJ, Kim DO, Shin DH, Kim YJ. Health-promoting effects of bovine colostrum in Type 2 diabetic patients can reduce blood glucose, cholesterol, triglyceride and ketones. J Nutr Biochem. 2009 Apr;20(4):298-303. doi: 10.1016/j.jnutbio.2008.04.002. Epub 2008 Jul 7.

Reference Type BACKGROUND
PMID: 18602824 (View on PubMed)

Other Identifiers

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4811344-HMO-CTIL

Identifier Type: -

Identifier Source: org_study_id