Trial Outcomes & Findings for Internet Self-Management Program With Telephone Support for Adolescents With Arthritis (NCT NCT01011179)

NCT ID: NCT01011179

Last Updated: 2021-03-29

Results Overview

The questionnaire is divided into 4 dimensions: gross motor function, fine motor function, psychosocial function, and general symptoms. A 7-point ordinal scale is used to rate responses to each item from 1 (none of the time) to 7 (all of the time), based on how often the item was a problem for the child over the past 2 weeks. Total score was composed of the 4 dimension scores (top 5 items of that dimension) divided by 4, with higher scores denoting poorer HRQOL.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

46 participants

Primary outcome timeframe

Baseline (prior to randomization) and 3 months after intervention

Results posted on

2021-03-29

Participant Flow

Participants were recruited from 4 pediatric, rheumatology clinics located within tertiary care centers across Canada. Adolescent participants were recruited between October and November 2008.

Participant milestones

Participant milestones
Measure
Attention Control Group
Self-Management : Adolescents' "own best efforts" at managing their JIA
Internet-based JIA Self-Management Program
Teens Taking Charge : The intervention is a 12-week multi-component treatment protocol that consists of self-management strategies (e.g., how to deal with stress and treatment related symptoms like pain), information (e.g., common problems associated with treatment and disease) and social support (e.g., monitored discussion boards and narratives in the form of written stories and video clips). It will be delivered on a restricted web-site and through regular contact with a trained coach by means of email and/or telephone using standardized scripts.
Overall Study
STARTED
24
22
Overall Study
COMPLETED
20
20
Overall Study
NOT COMPLETED
4
2

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Internet Self-Management Program With Telephone Support for Adolescents With Arthritis

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Attention Control Group
n=24 Participants
Self-Management : Adolescents' "own best efforts" at managing their JIA
Internet-based JIA Self-Management Program
n=22 Participants
Teens Taking Charge : The intervention is a 12-week multi-component treatment protocol that consists of self-management strategies (e.g., how to deal with stress and treatment related symptoms like pain), information (e.g., common problems associated with treatment and disease) and social support (e.g., monitored discussion boards and narratives in the form of written stories and video clips). It will be delivered on a restricted web-site and through regular contact with a trained coach by means of email and/or telephone using standardized scripts.
Total
n=46 Participants
Total of all reporting groups
Age, Categorical
<=18 years
24 Participants
n=5 Participants
22 Participants
n=7 Participants
46 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Sex: Female, Male
Female
16 Participants
n=5 Participants
15 Participants
n=7 Participants
31 Participants
n=5 Participants
Sex: Female, Male
Male
8 Participants
n=5 Participants
7 Participants
n=7 Participants
15 Participants
n=5 Participants
Region of Enrollment
Canada
24 participants
n=5 Participants
22 participants
n=7 Participants
46 participants
n=5 Participants

PRIMARY outcome

Timeframe: Baseline (prior to randomization) and 3 months after intervention

The questionnaire is divided into 4 dimensions: gross motor function, fine motor function, psychosocial function, and general symptoms. A 7-point ordinal scale is used to rate responses to each item from 1 (none of the time) to 7 (all of the time), based on how often the item was a problem for the child over the past 2 weeks. Total score was composed of the 4 dimension scores (top 5 items of that dimension) divided by 4, with higher scores denoting poorer HRQOL.

Outcome measures

Outcome measures
Measure
Internet-based JIA Self-Management Program
n=22 Participants
Teens Taking Charge: The intervention is a 12-week multi-component treatment protocol that consists of self-management strategies (e.g., how to deal with stress and treatment related symptoms like pain), information (e.g., common problems associated with treatment and disease) and social support (e.g., monitored discussion boards and narratives in the form of written stories and video clips). It will be delivered on a restricted web-site and through regular contact with a trained coach by means of email and/or telephone using standardized scripts.
Attention Control Group
n=24 Participants
Self-Management: Adolescents' "own best efforts" at managing their JIA
Juvenile Arthritis Quality of Life Questionnaire (JAQQ)
Baseline
2.35 units on a scale
Standard Deviation 1.34
2.74 units on a scale
Standard Deviation 1.36
Juvenile Arthritis Quality of Life Questionnaire (JAQQ)
Post-intervention
1.95 units on a scale
Standard Deviation 1.40
2.27 units on a scale
Standard Deviation 1.21

SECONDARY outcome

Timeframe: 3 months after intervention

Measure looks at disease specific knowledge. Subscale used: Medical Issues Subscale scores range from 0 (min) - 10 (max) with higher scores indicating greater knowledge.

Outcome measures

Outcome measures
Measure
Internet-based JIA Self-Management Program
n=24 Participants
Teens Taking Charge: The intervention is a 12-week multi-component treatment protocol that consists of self-management strategies (e.g., how to deal with stress and treatment related symptoms like pain), information (e.g., common problems associated with treatment and disease) and social support (e.g., monitored discussion boards and narratives in the form of written stories and video clips). It will be delivered on a restricted web-site and through regular contact with a trained coach by means of email and/or telephone using standardized scripts.
Attention Control Group
n=22 Participants
Self-Management: Adolescents' "own best efforts" at managing their JIA
Medical Issues Sub-Scale From Medical Issues, Exercise, Pain, and Social Support Questionnaire (MEPS)
4.16 score on a scale
Standard Deviation 1.96
6.98 score on a scale
Standard Deviation 1.08

SECONDARY outcome

Timeframe: Baseline (prior to randomization) and 3 months after intervention

Population: Data was not collected for this measure

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 3 months after intervention

Measure looks at Self-efficacy. Subscales: Activity, Emotion, Family. Subscale scores range 0 - 10 with higher scores indicating greater self-efficacy.

Outcome measures

Outcome measures
Measure
Internet-based JIA Self-Management Program
n=24 Participants
Teens Taking Charge: The intervention is a 12-week multi-component treatment protocol that consists of self-management strategies (e.g., how to deal with stress and treatment related symptoms like pain), information (e.g., common problems associated with treatment and disease) and social support (e.g., monitored discussion boards and narratives in the form of written stories and video clips). It will be delivered on a restricted web-site and through regular contact with a trained coach by means of email and/or telephone using standardized scripts.
Attention Control Group
n=22 Participants
Self-Management: Adolescents' "own best efforts" at managing their JIA
Children's Arthritis Self-Efficacy Scale (CASE)
Symptom Standard Score
6.55 score on a scale
Standard Deviation 2.75
7.47 score on a scale
Standard Deviation 1.89
Children's Arthritis Self-Efficacy Scale (CASE)
Emotional Standard Score
8.11 score on a scale
Standard Deviation 2.22
7.96 score on a scale
Standard Deviation 2.38
Children's Arthritis Self-Efficacy Scale (CASE)
Activity Standard Score
7.60 score on a scale
Standard Deviation 2.72
7.88 score on a scale
Standard Deviation 2.42

SECONDARY outcome

Timeframe: 3 months after intervention

Measure examines adherence to treatment. Subscales: Treatment Adherence to: Medication, Exercise, Splints. Subscale scores rage 0 - 10 with higher scores indicate better overall child ability in relation to following treatment recommendations.

Outcome measures

Outcome measures
Measure
Internet-based JIA Self-Management Program
n=24 Participants
Teens Taking Charge: The intervention is a 12-week multi-component treatment protocol that consists of self-management strategies (e.g., how to deal with stress and treatment related symptoms like pain), information (e.g., common problems associated with treatment and disease) and social support (e.g., monitored discussion boards and narratives in the form of written stories and video clips). It will be delivered on a restricted web-site and through regular contact with a trained coach by means of email and/or telephone using standardized scripts.
Attention Control Group
n=22 Participants
Self-Management: Adolescents' "own best efforts" at managing their JIA
Child Adherence Report Questionnaire (CARQ)
Medication
7.5 score on a scale
Standard Deviation 2.96
8.14 score on a scale
Standard Deviation 8.14
Child Adherence Report Questionnaire (CARQ)
Exercise
4.68 score on a scale
Standard Deviation 3.26
5.05 score on a scale
Standard Deviation 3.78

SECONDARY outcome

Timeframe: 3 months after intervention

Measure examines stress. Total score calculated was an average of all items with a range from 1-4 with higher scores indicating greater stress.

Outcome measures

Outcome measures
Measure
Internet-based JIA Self-Management Program
n=24 Participants
Teens Taking Charge: The intervention is a 12-week multi-component treatment protocol that consists of self-management strategies (e.g., how to deal with stress and treatment related symptoms like pain), information (e.g., common problems associated with treatment and disease) and social support (e.g., monitored discussion boards and narratives in the form of written stories and video clips). It will be delivered on a restricted web-site and through regular contact with a trained coach by means of email and/or telephone using standardized scripts.
Attention Control Group
n=22 Participants
Self-Management: Adolescents' "own best efforts" at managing their JIA
Perceived Stress Questionnaire (PSQ)
2.13 score on a scale
Standard Deviation 0.42
1.98 score on a scale
Standard Deviation 0.42

Adverse Events

Attention Control Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Internet-based JIA Self-Management Program

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Jennifer Stinson

The Hospital for Sick Children

Phone: 416-813-7654

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place