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Different Metabolic Effects of Statins

NCT ID: NCT01011127

Last Updated: 2010-10-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Study Classification

OBSERVATIONAL

Study Start Date

2009-12-31

Study Completion Date

2010-08-31

Brief Summary

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The investigators hypothesize that pravastatin and rosuvastatin may have different metabolic effects in hypercholesterolemic patients.

Detailed Description

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Conditions

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Hypercholesterolemia

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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pravastatin

pravastatin, rosuvastatin

Intervention Type DRUG

rosuvastatin

pravastatin, rosuvastatin

Intervention Type DRUG

Interventions

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pravastatin, rosuvastatin

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Low-density lipoprotein cholesterol levels\>130

Exclusion Criteria

* Overt liver disease Chronic renal failure Hypothyroidism Myopathy Uncontrolled diabetes Severe hypertension
Minimum Eligible Age

25 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Gachon University Gil Medical Center

OTHER

Sponsor Role lead

Locations

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Gil Medical Center

Incheon, , South Korea

Site Status

Countries

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South Korea

References

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Yada T, Nakata M, Shiraishi T, Kakei M. Inhibition by simvastatin, but not pravastatin, of glucose-induced cytosolic Ca2+ signalling and insulin secretion due to blockade of L-type Ca2+ channels in rat islet beta-cells. Br J Pharmacol. 1999 Mar;126(5):1205-13. doi: 10.1038/sj.bjp.0702397.

Reference Type BACKGROUND
PMID: 10205010 (View on PubMed)

Other Identifiers

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GMC-200914

Identifier Type: -

Identifier Source: org_study_id