Home
Clinical Trials
A Study of Chicory for Treatm...

A Study of Chicory for Treatment of Osteoarthritis of the Hip or Knee

Last Updated: 2009-11-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Study Classification

INTERVENTIONAL

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Extracts of chicory root have anti-inflammatory properties in vitro and in animal models of arthritis. The primary objective of this investigator-initiated, Phase 1, placebo-controlled, double blind, dose-escalating trial is to determine the safety and tolerability of a proprietary bioactive extract of chicory root in patients with osteoarthritis (OA). Secondary objectives are to assess effects on the signs and symptoms of this disorder. Individuals greater than 50 years of age with OA of the hip or knee will be eligible for trial entry.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Effects of Anthriscus Sylvestris Leaves on Mild Knee Osteoarthritis

NCT06535204

Osteoarthritis Articular Cartilage Functional Food

COMPLETED NA

A Double-blind, Randomized, Parallel Group, Fase III Comparative Study With Rose Hip Powder Powder and Placebo Given to Patients With Mild to Moderate Osteoarthritis in the Knee or/and Hip

NCT01459939

Pain Activities of Daily Living Quality of Life

COMPLETED PHASE3

Effectiveness and Safety of Sphaeralcea Angustifolia Standardized Extract as a Topical Treatment of Knee Osteoarthritis

NCT04511195

Knee Osteoarthritis

UNKNOWN PHASE2

The Efficacy of TGF for Treating Osteoarthritis of the Knee

NCT03562429

Osteoarthritis, Knee

UNKNOWN PHASE2/PHASE3

Efficacy and Safety of a New Formulation of Chondroitin Sulfate and Glucosamine Sulfate to Treat Knee Osteoarthritis

NCT01893905

Knee Osteoarthritis

COMPLETED PHASE3

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Osteoarthritis

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Chicory root extract

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Patients must be 50 years of age or older and may be of either gender.
2. Patients must have have an imaging-confirmed (radiograph or MRI) diagnosis of OA of the hip or knee.
3. Patients must not have taken a nonsteroidal anti-inflammatory medication for at least 7 days prior to the baseline visit (a single daily aspirin 325 mg or less is allowed throughout the study).
4. Patients must be able and willing to give informed consent.

Exclusion Criteria

1. Any unstable comorbid medical condition that in the opinion of the investigator could interfere with the ability of the patient to complete the study.
2. Patients who are unable to ambulate and require a wheelchair due to the severity of the arthritis are excluded. Ambulatory aids such as canes and walkers are acceptable.
3. Patients requiring continuing therapy with nonsteroidal anti-inflammatory drugs are excluded.
4. Patients requiring any dose of glucocorticoids within the past 30 days are excluded.

Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers