Effect of Dexamethasone Combined With Ondansetron on Postoperative Nausea and Vomiting in Patients With Patient-controlled Analgesia After Video-assisted Thoracoscopic Surgery
NCT ID: NCT01007500
Last Updated: 2016-12-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
123 participants
INTERVENTIONAL
2009-09-30
2010-09-30
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
DOUBLE
Study Groups
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Group Dexamethasone
Dexamethasone
Experimental: Dexamethasone 8 mg IV after induction of anesthesia, Ondansetron 4 mg IV at the end of surgery and 12 mg mix to intravenous patient controlled analgesia device.
Group Ondansetron
Ondansetron
Active comparator: Ondansetron 4 mg IV at the end of surgery and 12 mg mix to intravenous patient controlled analgesia device.
Interventions
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Dexamethasone
Experimental: Dexamethasone 8 mg IV after induction of anesthesia, Ondansetron 4 mg IV at the end of surgery and 12 mg mix to intravenous patient controlled analgesia device.
Ondansetron
Active comparator: Ondansetron 4 mg IV at the end of surgery and 12 mg mix to intravenous patient controlled analgesia device.
Eligibility Criteria
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Inclusion Criteria
* Age 20-75
* American Society of Anesthesiologists physical status classification I or II
Exclusion Criteria
* Taking Steroids, Opioids within 1 week
* Active drug or alcohol abuse
* GI motility disorder, severe renal/ hepatic disease.
20 Years
75 Years
ALL
No
Sponsors
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Yonsei University
OTHER
Responsible Party
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Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Reseach Institute, Yonsei University College of Medicine
Locations
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Severance Hospital, Yonsei University College of Medicine
Seoul, , South Korea
Countries
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Other Identifiers
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4-2009-0407
Identifier Type: -
Identifier Source: org_study_id