SIELLO Pilot Study for Comparison of Steroid Versus Non-Steroid Pacing Leads

NCT ID: NCT01000532

Last Updated: 2011-11-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

88 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-10-31

Study Completion Date

2011-02-28

Brief Summary

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This investigation is designed to demonstrate the clinical efficacy and safety of the low-dose drug of the SIELLO leads in comparison to the non-steroid BPPU leads in a clinical investigation.

Detailed Description

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Conditions

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Arrhythmias, Cardiac

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Pacemaker therapy

SIELLO JT/T

Intervention Type DEVICE

Implantation of SIELLO and BPPU pacemaker leads

Pacemaker therapy

Intervention Type DEVICE

Pacemaker therapy

BPPU JT/T

Intervention Type DEVICE

Implantation of SIELLO and BPPU pacemaker leads

Interventions

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SIELLO JT/T

Implantation of SIELLO and BPPU pacemaker leads

Intervention Type DEVICE

Pacemaker therapy

Pacemaker therapy

Intervention Type DEVICE

BPPU JT/T

Implantation of SIELLO and BPPU pacemaker leads

Intervention Type DEVICE

Other Intervention Names

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BPPU JT/T

Eligibility Criteria

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Inclusion Criteria

* Meet the indications for pacemaker therapy
* Understand the nature of the procedure
* Give informed consent
* Able to complete all testing required by the clinical protocol
* Available for follow-up visits on a regular basis at the investigational site

Exclusion Criteria

* Meet none of the pacemaker indications
* Meet one or more of the contraindications
* Have a life expectancy of less than six months
* Cardiac surgery in the next six months
* Enrolled in another cardiac clinical investigation
* Have other medical devices that may interact with the implanted pacemaker
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Biotronik SE & Co. KG

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Béla Merkely, Professor

Role: PRINCIPAL_INVESTIGATOR

Semmelweis University Heart Center, Budapest, Hungary

Locations

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Semmelweis University

Budapest, , Hungary

Site Status

Countries

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Hungary

References

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Kutyifa V, Zima E, Molnar L, Kuehne C, Theiss S, Herrmann G, Geller L, Merkely B. Direct comparison of steroid and non-steroid eluting small surface pacing leads: randomized, multicenter clinical trial. Cardiol J. 2013;20(4):431-8. doi: 10.5603/CJ.2013.0103.

Reference Type DERIVED
PMID: 23913463 (View on PubMed)

Other Identifiers

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47-1

Identifier Type: -

Identifier Source: org_study_id