Pilot Study: Mindfulness-Based Cognitive Therapy as a Tool for Prophylactic Mood Stabilizing Therapy in Bipolar Disorder

NCT ID: NCT00999765

Last Updated: 2023-05-15

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 36 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2008-06-30
• Study Completion Date: 2012-12-31

Brief Summary

The purpose of this study is to evaluate the feasibility and short-term efficacy of MBCT as an add-on (i.e. patients must be stable with their regular mood stabilizing medication) for the maintenance therapy of bipolar disorder.

Conditions

Bipolar Disorder

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Bipolar Disorder - stable

Mindfulness-Based Cognitive Therapy

Intervention Type: BEHAVIORAL

eight-week (two hours a week) group therapy (8-12 patients per group)

Interventions

Mindfulness-Based Cognitive Therapy

eight-week (two hours a week) group therapy (8-12 patients per group)

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Males or females (>18 years old)
• Bipolar disorder (as per the Structured Clinical Interview for DSM Disorders (SCID)(22)), euthymic state: Complete remission for at least four weeks ((Montgomery and Asberg Rating Scale (MADRS) ≤ 6 and item-1 (depressed mood) = 0 and no suicidal ideations (MADRS(item-10) < 4)
• Must have had at least 3 depressive phases in the last 5 years
• Cooperative and willing to complete all the aspects of the study and especially the 45 minutes of exercise per day
• Must have completed a Secondary V (11th grade) education

Exclusion Criteria

• Other active psychiatric disorders (as per the SCID)
• Rapid cycling
• Bipolar disorder secondary to a medical condition or substance-induced mood disorder
• Suicidal ideations (MADRS(item 10)>3)
• Active i.e. unstable and/or untreated medical condition
• Substance abuse (defined as per DSM-IV) in the last four weeks
• CBT (No more than four sessions (ever))
• Previous participation in a psychoeducation group within the last 6 months
• Current other psychotherapy (more than once a month)
• Practice of meditation (more than once a month) during the last two years
• Practice of yoga (more than once a week) during the last year
• Previous participation in a MBSR group
• Electroconvulsive Therapy (ECT) within the last three months

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Douglas Mental Health University Institute

OTHER

Sponsor Role: lead

Responsible Party

Serge Beaulieu

Serge Beaulieu

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Serge Beaulieu, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Douglas Mental Health University Institute / McGill

Locations

Douglas Mental Health University Institute

Montreal, Quebec, Canada

Countries

Canada

Other Identifiers

BD-MBCT

Identifier Type: -

Identifier Source: org_study_id